Nobiletin

Modify Date: 2024-01-02 19:45:19

Use of Nobiletin

Nobiletin is a citrus flavonoid with anti-inflammatory, anti-cancer, cholesterol lowering, memory protection activities.

Name	nobiletin
Synonym	More Synonyms

Description	Nobiletin is a citrus flavonoid with anti-inflammatory, anti-cancer, cholesterol lowering, memory protection activities.
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Cancer Natural Products >> Flavonoids
References	[1]. Takito J, et al. Nerve growth factor enhances the CRE-dependent transcriptional activity activated by nobiletin in PC12 cells. Can J Physiol Pharmacol. 2016 Feb 12:1-6. [2]. He B, et al. The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome. Cell Metab. 2016 Apr 12;23(4):610-21. [3]. Cheng HL, et al. Nobiletin inhibits human osteosarcoma cells metastasis by blocking ERK and JNK-mediated MMPs expression. Oncotarget. 2016 Apr 29.

Description

Nobiletin is a citrus flavonoid with anti-inflammatory, anti-cancer, cholesterol lowering, memory protection activities.

Related Catalog

Signaling Pathways >> Autophagy >> Autophagy

Research Areas >> Cancer

Natural Products >> Flavonoids

References

Density	1.2±0.1 g/cm3
Boiling Point	587.9±50.0 °C at 760 mmHg
Melting Point	138 °C
Molecular Formula	C₂₁H₂₂O₈
Molecular Weight	402.395
Flash Point	256.5±30.2 °C
Exact Mass	402.131470
PSA	85.59000
LogP	2.48
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.558
Storage condition	-20°C
Stability	Stable, but unstable if heated rapidly. Combustible. Incompatible with strong oxidizing agents, powdered aluminium, potassium.

Risk Phrases	R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S26-S36/37/39

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