2(5H)-Furanone

Modify Date: 2025-08-25 19:06:54

2(5H)-Furanone Structure
2(5H)-Furanone structure
 Common Name 2(5H)-Furanone
CAS Number 497-23-4 Molecular Weight 84.073
Density 1.2±0.1 g/cm3 Boiling Point 203.7±0.0 °C at 760 mmHg
Molecular Formula C4H4O2 Melting Point 4-5 °C(lit.)
MSDS Chinese USA Flash Point 101.1±0.0 °C

 Use of 2(5H)-Furanone


2(5H)-Furanone is an endogenous metabolite.

 Names

Name but-2-en-4-olide
Synonym More Synonyms

 2(5H)-Furanone Biological Activity

Description 2(5H)-Furanone is an endogenous metabolite.
Related Catalog

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 203.7±0.0 °C at 760 mmHg
Melting Point 4-5 °C(lit.)
Molecular Formula C4H4O2
Molecular Weight 84.073
Flash Point 101.1±0.0 °C
Exact Mass 84.021126
PSA 26.30000
LogP -0.84
Vapour Pressure 0.3±0.4 mmHg at 25°C
Index of Refraction 1.481
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LU3453000
CHEMICAL NAME :
2(5H)-Furanone
CAS REGISTRY NUMBER :
497-23-4
BEILSTEIN REFERENCE NO. :
0383585
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C4-H4-O2
MOLECULAR WEIGHT :
84.08

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
1400 mg/kg
SEX/DURATION :
female 2 week(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 123,571,1990
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
1400 mg/kg
SEX/DURATION :
female 2 week(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - other effects Endocrine - changes in luteinizing hormone
REFERENCE :
ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 123,571,1990

 Safety Information

Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS LU3453000
Packaging Group I; II; III
HS Code 29322980

 Synthetic Route

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles41

More Articles
Comparative safety of the antifouling compound butenolide and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) to the marine medaka (Oryzias melastigma).

Aquat. Toxicol. 149 , 116-25, (2014)

This study evaluated the potential adverse effects of butenolide, a promising antifouling compound, using the marine medaka (Oryzias melastigma), a model fish for marine ecotoxicology. The active ingr...

Proteomic changes in brain tissues of marine medaka (Oryzias melastigma) after chronic exposure to two antifouling compounds: butenolide and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT).

Aquat. Toxicol. 157 , 47-56, (2014)

SeaNine 211 with active ingredient of 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) has been used as a "green" antifouling agent worldwide but has raised serious biosafety concerns in coastal en...

Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death.

Toxicol. Lett. 222(1) , 64-71, (2013)

The alpha, beta-unsaturated lactones 2-furanone and 2-pyrone are part of the chemical structure of a variety of naturally occurring compounds (e.g., cardenolides, bufadienolides, acetogenins, coumarin...

 Synonyms

5-Hydrofuran-2-one
Furan-2(5H)-one
4-Hydroxycrotonic acid γ-lactone
2H-furan-5-one
2-Butenoic acid-γ-lactone
EINECS 207-839-3
T5OV EHJ
2-Butenoic acid γ-lactone
2(5H)-Furanone
MFCD00005376
2[5H]-furanone
4-Hydroxy-2-butenoic acid γ-lactone
γ-Crotonolactone
2-Buten-1,4-olide
2-Oxo-2,5-dihydrofuran
2-Butenoic acid, 4-hydroxy-, γ-lactone
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Chemsrc provides 2(5H)-Furanone(CAS#:497-23-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 2(5H)-Furanone are included as well.>> amp version: 2(5H)-Furanone

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