Schaftoside
Schaftoside structure
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Common Name | Schaftoside | ||
|---|---|---|---|---|
| CAS Number | 51938-32-0 | Molecular Weight | 564.49 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | 1028.2±65.0 °C at 760 mmHg | |
| Molecular Formula | C26H28O14 | Melting Point | 228ºC | |
| MSDS | Chinese USA | Flash Point | 342.7±27.8 °C | |
Use of SchaftosideSchaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission[1]. |
Summary: Schaftoside, Chinese name: 夏佛塔苷, CAS number: 51938-32-0, molecular formula: C26H28O14, molecular weight: 564.49. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | schaftoside |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Schaftoside inhibits three pro-inflammatory enzymatic activities: secretory phospholipase A2 (sPLA2), lipoxygenase (LOX), and cyclooxygenase 2 (COX-2). Schaftoside also inhibits mRNA and protein expressions of proinflammatory cytokines(IL-1β, TNF-α, and IL-6)[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 1028.2±65.0 °C at 760 mmHg |
| Melting Point | 228ºC |
| Molecular Formula | C26H28O14 |
| Molecular Weight | 564.49 |
| Flash Point | 342.7±27.8 °C |
| Exact Mass | 596.137756 |
| PSA | 269.43000 |
| LogP | -3.06 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.754 |
| InChIKey | MMDUKUSNQNWVET-VYUBKLCTSA-N |
| SMILES | O=c1cc(-c2ccc(O)cc2)oc2c(C3OCC(O)C(O)C3O)c(O)c(C3OC(CO)C(O)C(O)C3O)c(O)c12 |
| Storage condition | 2-8°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Safety Phrases | 24/25 |
|---|---|
| RIDADR | NONH for all modes of transport |
| RTECS | DJ2977250 |
| HS Code | 29389090 |
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Shaftoside |
| Apigenin 8-C-|A-L-arabinoside 6-C-|A-D-glucoside |
| Schaftoside |
| 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]chromen-4-one |
| 8-(D-Arabinopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl D-glucopyranoside |
| schaftozide |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the uses of schaftoside? |
| A: Main uses of schaftoside: Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission[1]. |
| Q: What is the LogP of schaftoside? |
| A: LogP of schaftoside is -3.06. |
| Q: What is the molecular formula of schaftoside? |
| A: Molecular formula of schaftoside is C26H28O14. |
| Q: What is the SMILES notation of schaftoside? |
| A: SMILES notation of schaftoside is O=c1cc(-c2ccc(O)cc2)oc2c(C3OCC(O)C(O)C3O)c(O)c(C3OC(CO)C(O)C(O)C3O)c(O)c12. |
| Q: What is the InChIKey of schaftoside? |
| A: InChIKey of schaftoside is MMDUKUSNQNWVET-VYUBKLCTSA-N. |
| Q: What is the safety information for schaftoside? |
| A: Safety information for schaftoside: 24/25. |
| Q: What English synonyms does schaftoside have? |
| A: English synonyms of schaftoside: Shaftoside, Apigenin 8-C-|A-L-arabinoside 6-C-|A-D-glucoside, Schaftoside, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]chromen-4-one, 8-(D-Arabinopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-6-yl D-glucopyranoside, schaftozide. |
| Q: What is the CAS number of schaftoside? |
| A: CAS number of schaftoside is 51938-32-0. |
| Q: What are the storage conditions for schaftoside? |
| A: Storage conditions for schaftoside: 2-8°C. |
| Q: What is the melting point of schaftoside? |
| A: Melting point of schaftoside is 228ºC. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| naturewill |