Chloro-PEG5-chloride
Modify Date: 2024-01-16 12:27:49
Chloro-PEG5-chloride structure
|
Common Name | Chloro-PEG5-chloride | ||
|---|---|---|---|---|
| CAS Number | 5197-65-9 | Molecular Weight | 275.16900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H20Cl2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Chloro-PEG5-chlorideChloro-PEG5-chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 1,2-bis[2-(2-chloroethoxy)ethoxy]ethane |
|---|---|
| Synonym | More Synonyms |
| Description | Chloro-PEG5-chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C10H20Cl2O4 |
|---|---|
| Molecular Weight | 275.16900 |
| Exact Mass | 274.07400 |
| PSA | 36.92000 |
| LogP | 1.53040 |
|
~89%
Chloro-PEG5-chloride CAS#:5197-65-9 |
| Literature: Rey, Jimena; Garcia, Felix Clemente; Garcia, Jose Miguel Reactive and Functional Polymers, 2011 , vol. 71, # 9 p. 948 - 957 |
|
~%
Chloro-PEG5-chloride CAS#:5197-65-9 |
| Literature: Prelog,V.; Bedekovic,D. Helvetica Chimica Acta, 1979 , vol. 62, p. 2285 - 2303 |
| Precursor 2 | |
|---|---|
| DownStream 10 | |
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