HO-PEG5-CH2COOH

Modify Date: 2025-08-25 11:27:09

HO-PEG5-CH2COOH Structure
HO-PEG5-CH2COOH structure
Common Name HO-PEG5-CH2COOH
CAS Number 52026-48-9 Molecular Weight 296.31
Density N/A Boiling Point N/A
Molecular Formula C12H24O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HO-PEG5-CH2COOH


HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name HO-PEG5-CH2COOH
Synonym More Synonyms

 HO-PEG5-CH2COOH Biological Activity

Description HO-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H24O8
Molecular Weight 296.31

 Synonyms

MFCD31656910
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