Harmalane

Modify Date: 2025-08-25 18:19:52

Harmalane Structure
Harmalane structure
Common Name Harmalane
CAS Number 525-41-7 Molecular Weight 184.24
Density 1.23g/cm3 Boiling Point 390.3ºC at 760mmHg
Molecular Formula C12H12N2 Melting Point N/A
MSDS N/A Flash Point 189.9ºC

 Use of Harmalane


Harmalan (compound 8) is a alkaloid isolated from the extracts of the leaves of Flindersia laevicarpa[1].

 Names

Name 1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole
Synonym More Synonyms

 Harmalane Biological Activity

Description Harmalan (compound 8) is a alkaloid isolated from the extracts of the leaves of Flindersia laevicarpa[1].
Related Catalog
References

[1]. K Picker, et al. The chemical constituents of Australian Flindersia species. XXI. An examination of the bark and the leaves of F. laevicarpa. Australian Journal of Chemistry. 2009, 29, 9.

 Chemical & Physical Properties

Density 1.23g/cm3
Boiling Point 390.3ºC at 760mmHg
Molecular Formula C12H12N2
Molecular Weight 184.24
Flash Point 189.9ºC
Exact Mass 184.10000
PSA 24.39000
LogP 0.45970
Index of Refraction 1.678

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Synthetic Route

~88%

Harmalane Structure

Harmalane

CAS#:525-41-7

Literature: Ghislieri, Diego; Green, Anthony P.; Pontini, Marta; Willies, Simon C.; Rowles, Ian; Frank, Annika; Grogan, Gideon; Turner, Nicholas J. Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10863 - 10869

~64%

Harmalane Structure

Harmalane

CAS#:525-41-7

Literature: Diem, Stefanie; Gutsche, Birgit; Herderich, Markus Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 12 p. 5993 - 5998

~75%

Harmalane Structure

Harmalane

CAS#:525-41-7

Literature: Ivanov, Iliyan; Nikolova, Stoyanka; Statkova-Abeghe, Stela Heterocycles, 2005 , vol. 65, # 10 p. 2483 - 2492

~%

Harmalane Structure

Harmalane

CAS#:525-41-7

Literature: Bobowski; Shavel Jr. Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 6 p. 1679 - 1688

~%

Harmalane Structure

Harmalane

CAS#:525-41-7

Literature: Bobowski, George Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 267 - 272

~%

Harmalane Structure

Harmalane

CAS#:525-41-7

Literature: Bobowski; Shavel Jr. Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 6 p. 1679 - 1688

~%

Harmalane Structure

Harmalane

CAS#:525-41-7

Literature: Bobbitt, James M.; Willis, John P. Journal of Organic Chemistry, 1980 , vol. 45, # 10 p. 1978 - 1984

~%

Harmalane Structure

Harmalane

CAS#:525-41-7

Literature: Spenser Canadian Journal of Chemistry, 1959 , vol. 37, p. 1851,1856

~%

Harmalane Structure

Harmalane

CAS#:525-41-7

Literature: Spaeth; Lederer Chemische Berichte, 1930 , vol. 63, p. 120,123

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 HarmalaneBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Confirmed inhibitors of the Choline Transporter (CHT)
Source: 1043
Target: high affinity choline transporter 1 [Homo sapiens]
External Id: SAID_488997
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 Synonyms

Harmalan
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