Sesamolin
Sesamolin structure
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Common Name | Sesamolin | ||
|---|---|---|---|---|
| CAS Number | 526-07-8 | Molecular Weight | 370.353 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 520.8±50.0 °C at 760 mmHg | |
| Molecular Formula | C20H18O7 | Melting Point | 93 - 94ºC (Decomposes) | |
| MSDS | N/A | Flash Point | 219.2±30.0 °C | |
Use of SesamolinSesaminol, isolated from Justicia orbiculata, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect. Sesaminol potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression[1][2][3][4]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | sesamolin |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Sesaminol, isolated from Justicia orbiculata, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect. Sesaminol potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression[1][2][3][4]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 520.8±50.0 °C at 760 mmHg |
| Melting Point | 93 - 94ºC (Decomposes) |
| Molecular Formula | C20H18O7 |
| Molecular Weight | 370.353 |
| Flash Point | 219.2±30.0 °C |
| Exact Mass | 370.105255 |
| PSA | 64.61000 |
| LogP | 2.88 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.622 |
| InChIKey | ZZMNWJVJUKMZJY-AFHBHXEDSA-N |
| SMILES | c1cc2c(cc1OC1OCC3C(c4ccc5c(c4)OCO5)OCC13)OCO2 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Hazard Codes | Xi |
|---|---|
| WGK Germany | 3.0 |
| HS Code | 29329990 |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of rat intestinal sucrase using sucrose as substrate at 10 mg/ml preincuba...
Source: ChEMBL
Target: Sucrase-isomaltase, intestinal
External Id: CHEMBL2061354
|
|
Name: Inhibition of Wnt/beta-catenin signaling pathway in human HEK293 cells at 20 uM after...
Source: ChEMBL
Target: HEK293
External Id: CHEMBL2445921
|
|
Name: Inhibition of rat intestinal maltase using maltose as substrate at 10 mg/ml preincuba...
Source: ChEMBL
Target: Lysosomal alpha-glucosidase
External Id: CHEMBL2061356
|
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]fur-1-yl]-1,3-benzodioxol |
| 5-[(1S,3aR,4R,6aR)-4-(2H-1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2H-1,3-benzodioxole |
| Sesamolin |
| 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole |
| (1S,3aR,4R,6aR)-5-[4-(1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole |
| 5-[4-(1,3-Benzodioxolol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole |
| 1,3-benzodioxol-5-yl (1R,3aR,4S,6aR)-4-(1,3-benzodioxol-5-yl)perhydrofuro[3,4-c]furan-1-yl ether |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of sesamolin? |
| A: Polar surface area (PSA) of sesamolin is 64.61000. |
| Q: What is the CAS number of sesamolin? |
| A: CAS number of sesamolin is 526-07-8. |
| Q: What is the English name of sesamolin? |
| A: The English name of sesamolin is sesamolin. |
| Q: What is the LogP of sesamolin? |
| A: LogP of sesamolin is 2.88. |
| Q: What are the uses of sesamolin? |
| A: Main uses of sesamolin: Sesaminol, isolated from Justicia orbiculata, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect. Sesaminol potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression[1][2][3][4]. |
| Q: What is the SMILES notation of sesamolin? |
| A: SMILES notation of sesamolin is c1cc2c(cc1OC1OCC3C(c4ccc5c(c4)OCO5)OCC13)OCO2. |
| Q: What is the molecular formula of sesamolin? |
| A: Molecular formula of sesamolin is C20H18O7. |
| Q: What is the melting point of sesamolin? |
| A: Melting point of sesamolin is 93 - 94ºC (Decomposes). |
| Q: What is the molecular weight of sesamolin? |
| A: Molecular weight of sesamolin is 370.353. |
| Q: What is the InChIKey of sesamolin? |
| A: InChIKey of sesamolin is ZZMNWJVJUKMZJY-AFHBHXEDSA-N. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| naturewill |