Scutellarein
Scutellarein structure
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Common Name | Scutellarein | ||
|---|---|---|---|---|
| CAS Number | 529-53-3 | Molecular Weight | 286.236 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 642.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C15H10O6 | Melting Point | 330ºC | |
| MSDS | Chinese USA | Flash Point | 249.9±25.0 °C | |
Use of ScutellareinScutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz., has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Scutellarein |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Scutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz., has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 642.9±55.0 °C at 760 mmHg |
| Melting Point | 330ºC |
| Molecular Formula | C15H10O6 |
| Molecular Weight | 286.236 |
| Flash Point | 249.9±25.0 °C |
| Exact Mass | 286.047729 |
| PSA | 111.13000 |
| LogP | 2.54 |
| Appearance of Characters | yellow |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.768 |
| InChIKey | JVXZRQGOGOXCEC-UHFFFAOYSA-N |
| SMILES | O=c1cc(-c2ccc(O)cc2)oc2cc(O)c(O)c(O)c12 |
| Storage condition | 2-8°C |
| Water Solubility | DMSO: soluble1mg/mL, clear, greenish-yellow |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Safety Phrases | 24/25 |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2914501900 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 9 | |
|---|---|
| DownStream 10 | |
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CAS#:88-89-1This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2914501900 |
|---|---|
| Summary | 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Delineation of Platelet Activation Pathway of Scutellarein Revealed Its Intracellular Target as Protein Kinase C.
Biol. Pharm. Bull. 39 , 181-91, (2016) Erigeron breviscapus has been widely used in traditional Chinese medicine (TCM) and its total flavonoid component is commonly used to treat ischemic stroke, coronary heart disease, diabetes and hypert... |
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Liquid Chromatography-Tandem Mass Spectrometry Screening Method for the Detection of Radical-Scavenging Natural Antioxidants from the Whole Scutellariae (Radix, Stem and Leaf).
J. Chromatogr. Sci. 53 , 1140-6, (2015) A novel free radical reaction combined with high-performance LC-photodiode array-ESI-MS/MS screening method was developed for the detection and identification of natural antioxidants from whole Scutel... |
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Effect of light, methyl jasmonate and cyclodextrin on production of polyphenolic compounds in hairy root cultures of Scutellaria lateriflora
Phytochemistry 107 , 50-60, (2014) Graphical abstract [Display omitted] |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of human OATP2B1 expressed in Flp-In-CHO cells assessed as inhibition of O...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 2B1
External Id: CHEMBL5260630
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Name: Inhibition of human OATP2B1 expressed in Flp-In-CHO cells assessed as inhibition of O...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 2B1
External Id: CHEMBL5260629
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Name: Inhibition of human OATP2B1 expressed in Flp-In-CHO cells assessed as inhibition of O...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 2B1
External Id: CHEMBL5260631
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Name: Solubility of compound in water at 0.1 to 10 ug/ml by UV spectrophotometry relative t...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3636113
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Name: Antioxidant activity assessed as DDPH radical scavenging activity
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL1225535
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Name: Solubility of compound in water at 0.1 to 10 ug/ml by UV spectrophotometry
Source: ChEMBL
Target: N/A
External Id: CHEMBL3636112
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Name: Inhibition of HCV NS3 helicase overexpressed in Escherichia coli BL21(DE3) assessed a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2060535
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Name: Binding affinity towards benzodiazepine site in GABAA receptor
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit theta
External Id: CHEMBL877825
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Name: Inhibition of SARS coronavirus nsP13 ATP hydrolysis activity expressed in Escherichia...
Source: ChEMBL
Target: N/A
External Id: CHEMBL2060536
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Name: Inhibition of cow milk xanthine oxidase
Source: ChEMBL
Target: Xanthine dehydrogenase/oxidase
External Id: CHEMBL1015631
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one |
| 5,6,7,4'-tetrahydroxyflavone |
| 5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| 4',5,6,7-Tetrahydroxyflavanone |
| 6-Hydroxypelargidenon 1465 |
| Scutellarein |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the polar surface area (PSA) of Scutellarein? |
| A: Polar surface area (PSA) of Scutellarein is 111.13000. |
| Q: What is the boiling point of Scutellarein? |
| A: Boiling point of Scutellarein is 642.9±55.0 °C at 760 mmHg. |
| Q: What is the molecular formula of Scutellarein? |
| A: Molecular formula of Scutellarein is C15H10O6. |
| Q: How is the water solubility of Scutellarein? |
| A: Water solubility of Scutellarein: DMSO: soluble1mg/mL, clear, greenish-yellow. |
| Q: What is the SMILES notation of Scutellarein? |
| A: SMILES notation of Scutellarein is O=c1cc(-c2ccc(O)cc2)oc2cc(O)c(O)c(O)c12. |
| Q: What is the English name of Scutellarein? |
| A: The English name of Scutellarein is Scutellarein. |
| Q: What is the molecular weight of Scutellarein? |
| A: Molecular weight of Scutellarein is 286.236. |
| Q: What is the LogP of Scutellarein? |
| A: LogP of Scutellarein is 2.54. |
| Q: What is the safety information for Scutellarein? |
| A: Safety information for Scutellarein: 24/25. |
| Q: What English synonyms does Scutellarein have? |
| A: English synonyms of Scutellarein: 5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, 5,6,7,4'-tetrahydroxyflavone, 5,6,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4',5,6,7-Tetrahydroxyflavanone, 6-Hydroxypelargidenon 1465, Scutellarein. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| Dayang Chem (Hangzhou) Co., Ltd. |
| naturewill |