ar-Turmerone

Modify Date: 2026-07-01 15:00:56

ar-Turmerone structure	Common Name	ar-Turmerone
	CAS Number	532-65-0	Molecular Weight	216.31900
	Density	N/A	Boiling Point	326℃
	Molecular Formula	C₁₅H₂₀O	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07, GHS09	Signal Word	Warning

Use of ar-Turmerone

ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-turmerone ((+)-ar-Turmerone) activates apoptotic protein in human lymphoma U937 cells[3]. ar-Turmerone ((+)-ar-Turmerone) exerts positive modulation on murine DCs, induces NSC proliferation and constitutes a promising therapeutic agent for various neurologic disorders[4][5].

Name	(+)-(S)-ar-turmerone
Synonym	More Synonyms

Description	ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-turmerone ((+)-ar-Turmerone) activates apoptotic protein in human lymphoma U937 cells[3]. ar-Turmerone ((+)-ar-Turmerone) exerts positive modulation on murine DCs, induces NSC proliferation and constitutes a promising therapeutic agent for various neurologic disorders[4][5].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Inflammation/Immunology
References	[1]. Liju VB, et al. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011 Sep;43(5):526-31. [2]. Yue GG, et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2011-20. [3]. Lee Y, et al. Activation of apoptotic protein in U937 cells by a component of turmeric oil. BMB Rep. 2009 Feb 28;42(2):96-100. [4]. Yonggang T, et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR). Hum Vaccin Immunother. 2012 Oct;8(10):1416-24. [5]. Hucklenbroich J, et al. Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther. 2014 Sep 26;5(4):100.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

References

[1]. Liju VB, et al. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011 Sep;43(5):526-31.

[2]. Yue GG, et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2011-20.

[3]. Lee Y, et al. Activation of apoptotic protein in U937 cells by a component of turmeric oil. BMB Rep. 2009 Feb 28;42(2):96-100.

[4]. Yonggang T, et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR). Hum Vaccin Immunother. 2012 Oct;8(10):1416-24.

[5]. Hucklenbroich J, et al. Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther. 2014 Sep 26;5(4):100.

Boiling Point	326℃
Molecular Formula	C₁₅H₂₀O
Molecular Weight	216.31900
Exact Mass	216.15100
PSA	17.07000
LogP	4.02390
InChIKey	NAAJVHHFAXWBOK-ZDUSSCGKSA-N
SMILES	CC(C)=CC(=O)CC(C)c1ccc(C)cc1

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H317-H319-H411
Precautionary Statements	P273-P280-P305 + P351 + P338
Hazard Codes	Xi,N
Risk Phrases	36-43-51/53
Safety Phrases	36/37-61
RIDADR	UN 3082 9 / PGIII
HS Code	2914399090

(S)-3-(4-methyl...

CAS#:1201-85-0

ar-Turmerone

CAS#:532-65-0

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Literature: Sato, Toshio; Kawara, Tatsuo; Nishizawa, Akira; Fujisawa, Tamotsu Tetrahedron Letters, 1980 , vol. 21, p. 3377 - 3380

Precursor 1
CAS#:1201-85-0 (S)-3-(4-methyl...
DownStream 0

HS Code	2914399090
Summary	2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Turmeric (Curcuma longa L.) volatile oil inhibits key enzymes linked to type 2 diabetes.

Int. J. Food Sci. Nutr. 63(7) , 832-4, (2012)

Anti-diabetic capacity of Curcuma longa volatile oil in terms of its ability to inhibit glucosidase activities was evaluated. Turmeric volatile oils inhibited glucosidase enzymes more effectively than...

Selective induction of apoptosis by ar-turmerone isolated from turmeric (Curcuma longa L) in two human leukemia cell lines, but not in human stomach cancer cell line.

Int. J. Mol. Med. 9(5) , 481-4, (2002)

We have investigated the effects of ar-turmerone isolated from turmeric (Curcuma longa L) on DNA of human leukemia cell lines, Molt 4B, HL-60 and stomach cancer KATO III cells. It was found that selec...

Induction of apoptosis by ar-turmerone on various cell lines.

Int. J. Mol. Med. 14(2) , 253-6, (2004)

This study investigated the cytotoxic effect of ar-turmerone isolated from turmeric (Curcuma longa L) on the K562, L1210, U937 and RBL-2H3 cell lines by the MTT assay. Ar-turmerone exhibited potent cy...

Name: Cytotoxicity against human HaCaT-ARE-Luc cells assessed as cell viability at 1 to 50 ...
Source: ChEMBL
Target: HaCaT
External Id: CHEMBL3803095

Name: Cytotoxicity against human HeLa-STAT3-Luc cells assessed as cell viability at 1 to 50...
Source: ChEMBL
Target: HeLa
External Id: CHEMBL3803094

Name: Cytotoxicity against mouse NIH/3T3-EPO-Luc cells assessed as cell viability at 1 to 5...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3803093

Name: Cytotoxicity against mouse NIH/3T3-KBF-Luc cells assessed as cell viability at 1 to 5...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3802844

Name: Inhibition of DFX induced HIF-1 alpha (unknown origin) activation in NIH/3T3-EPO-Luc ...
Source: ChEMBL
Target: Hypoxia-inducible factor 1-alpha
External Id: CHEMBL3803097

Name: Activation of Nrf2 (unknown origin) in HaCaT-ARE-Luc cells at 1 to 50 uM after 6 hrs ...
Source: ChEMBL
Target: Nuclear factor erythroid 2-related factor 2
External Id: CHEMBL3803096

Name: Inhibition of TNF alpha-induced NF-kappaB (unknown origin) activation in NIH/3T3-KBF-...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3802843

Name: Inhibition of TNF alpha-induced NF-kappaB (unknown origin) activation in NIH/3T3-KBF-...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3802842

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Tumerone

(+)-ar-Turmerone

(S)-AR-TURMERONE

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China
Product Name: ar-Turmerone
Price: Check
Purity: 97.0%
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BioBioPha
China
Product Name: ar-Turmerone
Price: ￥1400.0/5mg
Purity: 97.0%
Delivery: 10 Day
Contact: Xueping-Zheng
Email: 1477035482@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ar-turmerone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.