(-)-Bicuculline methochloride
Modify Date: 2024-01-09 23:24:58
(-)-Bicuculline methochloride structure
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Common Name | (-)-Bicuculline methochloride | ||
|---|---|---|---|---|
| CAS Number | 53552-05-9 | Molecular Weight | 417.84000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H20ClNO6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (-)-Bicuculline methochloride(-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons[1]. |
| Name | 6-(6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl)-6H-furo[3,4-g][1,3]benzodioxol-8-one,chloride |
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| Description | (-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons[1]. |
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| Related Catalog | |
| Target |
GABAA[1] |
| In Vivo | (-)-Bicuculline methochloride (0.6 nmol/rat) attenuates the antiallodynic effect of Neurotropin[2]. Animal Model: Rat L5-SNL model[2] Dosage: 0.6 nmol/rat Administration: Intrathecal injection, 5 minutes before administration of Neurotropin (100 NU/kg, i.v.) Result: Attenuated the antiallodynic effect of Neurotropin. |
| References |
| Molecular Formula | C21H20ClNO6 |
|---|---|
| Molecular Weight | 417.84000 |
| Exact Mass | 417.09800 |
| PSA | 63.22000 |
- Shanghai Nianxing Industrial Co., Ltd
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- Product Name: (-)-Bicuculline methochloride
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- Product Name: (-)-Bicuculline methochloride
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- Product Name: (-)-Bicuculline methochloride
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- China
- Product Name: (4-CYANO-2-NITROPHENYL)BORONICACID
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