Uvaol

Modify Date: 2025-08-21 19:20:27

Uvaol structure	Common Name	Uvaol
	CAS Number	545-46-0	Molecular Weight	442.717
	Density	1.1±0.1 g/cm3	Boiling Point	523.7±50.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₅₀O₂	Melting Point	223-225ºC(lit.)
	MSDS	Chinese USA	Flash Point	211.6±24.7 °C

Use of Uvaol

Uvaol, a triterpene present in olives and virgin olive oil, possesses anti-inflammatory properties and antioxidant effects. Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice[1].

Name	uvaol
Synonym	More Synonyms

Description	Uvaol, a triterpene present in olives and virgin olive oil, possesses anti-inflammatory properties and antioxidant effects. Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Agra LC, et al. Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice. Eur J Pharmacol. 2016 Jun 5;780:232-42.

Density	1.1±0.1 g/cm3
Boiling Point	523.7±50.0 °C at 760 mmHg
Melting Point	223-225ºC(lit.)
Molecular Formula	C₃₀H₅₀O₂
Molecular Weight	442.717
Flash Point	211.6±24.7 °C
Exact Mass	442.381073
PSA	40.46000
LogP	9.13
Vapour Pressure	0.0±3.1 mmHg at 25°C
Index of Refraction	1.550
InChIKey	XUARCIYIVXVTAE-ZAPOICBTSA-N
SMILES	CC1CCC2(CO)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1C

Hazard Codes	Xi
Risk Phrases	R22
Safety Phrases	22-45
RIDADR	NONH for all modes of transport
WGK Germany	3

Ursolic Acid

CAS#:77-52-1

Uvaol

CAS#:545-46-0

Literature: Journal of the American Pharmaceutical Association (1912-1977), , vol. 39, p. 475

3-ACETYLOXY-(3B...

CAS#:990-89-6

Uvaol

CAS#:545-46-0

Literature: Zakaria, Muhamad Bin; Jeffreys, J. A. D.; Waterman, Peter G.; Zhong, Shou-Ming Phytochemistry (Elsevier), 1984 , vol. 23, # 7 p. 1481 - 1484

3-HYDROXY-(3ALP...

CAS#:915-32-2

Uvaol

CAS#:545-46-0

Literature: Collins, Dwight O.; Ruddock, Peter L. D.; Grasse, Jessica Chiverton de; Reynolds, William F.; Reese, Paul B. Phytochemistry (Elsevier), 2002 , vol. 59, # 5 p. 479 - 488

(3S,4aR,6aR,6bS...

CAS#:86360-96-5

Uvaol

CAS#:545-46-0

Literature: Majumder, P. L.; Bagchi, A. Tetrahedron, 1983 , vol. 39, # 4 p. 649 - 656

3β-acetoxyurs-1...

CAS#:86996-88-5

Uvaol

CAS#:545-46-0

Literature: Chemical and Pharmaceutical Bulletin, , vol. 31, # 5 p. 1567 - 1571

3-ACETYLOXY-(3A...

CAS#:915-79-7

Uvaol

CAS#:545-46-0

Literature: Chemical and Pharmaceutical Bulletin, , vol. 31, # 5 p. 1567 - 1571

3β-acetoxy-28-h...

CAS#:25089-86-5

Uvaol

CAS#:545-46-0

Literature: Chemical and Pharmaceutical Bulletin, , vol. 31, # 5 p. 1567 - 1571

N/A

CAS#:74984-68-2

Uvaol

CAS#:545-46-0

Literature: Journal of the American Pharmaceutical Association (1912-1977), , vol. 34, p. 39,40

Precursor 4
CAS#:77-52-1 Ursolic Acid CAS#:86360-96-5 (3S,4aR,6aR,6bS... CAS#:86996-88-5 3β-acetoxyurs-1... CAS#:25089-86-5 3β-acetoxy-28-h...
DownStream 0

Changes of the wax contents in mixtures of olive oils as determined by gas chromatography with a flame ionization detector.

J. AOAC Int. 95(6) , 1720-4, (2012)

Mixing of refined olive-pomace oil with virgin olive oil is a fraud that has been tried often. Normally, the tests that detected the fraud were determinations of wax esters, erythrodiol+uvaol, and sti...

Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells.

Cytokine 36(5-6) , 211-7, (2006)

Olive pomace oil, also known as "orujo" olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption. Maslinic acid, oleanolic acid, erythrodiol, and uvaol are pentacycl...

Study of skin anti-ageing and anti-inflammatory effects of dihydroquercetin, natural triterpenoids, and their synthetic derivatives.

Bioorg. Khim. 38(3) , 374-81, (2012)

Accessible triterpenoids of ursane and lupane series, the flavonoid dihydroquercetin and their synthetic derivatives with polar substituentss were tested in vitro for inhibition of collagenase 1 (MMP-...

Name: Cytotoxicity against human A549 cells assessed as cell viability after 24 hrs by MTT ...
Source: ChEMBL
Target: A549
External Id: CHEMBL980082

Name: Antiinflammatory activity against human A549 cells assessed as inhibition of IL-1-alp...
Source: ChEMBL
Target: A549
External Id: CHEMBL980081

Name: Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL5133480

Name: Inhibition of biotinylated consensus sequence binding to NF-kB p65 in human HeLa nucl...
Source: ChEMBL
Target: Transcription factor p65
External Id: CHEMBL4235015

Name: Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of HMGB1-in...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL5133481

Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS

Name: Cytotoxicity against human OVCAR3 cells assessed as reduction in cell viability after...
Source: ChEMBL
Target: OVCAR-3
External Id: CHEMBL4235014

Name: Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 50 uM
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL5133482

Name: Inhibition of mitochondrial membrane potential in human HT-29 cells after 3 hrs by JC...
Source: ChEMBL
Target: HT-29
External Id: CHEMBL4235016

Name: Antimicrobial activity against Pseudomonas aeruginosa by broth microdilution method
Source: ChEMBL
Target: Pseudomonas aeruginosa
External Id: CHEMBL969466

Total 75, Current Page 1 of 8

urs-12-ene-3,28-diol

(3S,4aR,6aR,6bS,8aS,11R,12S,12aS,14aR,14bR)-8a-(Hydroxymethyl)-4,4,6a,6b,11,12,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-3-picenol

urs-12-ene-3beta,28-diol

12-URSEN-3BETA,28 DIOL

3B,28-DIHYDROXY-URSA-12-EN

(3β)-Urs-12-ene-3,28-diol

12-URSEN-3B,28-DIOL

Uvaol,Urs-12-ene-3,28-diol

(3S,4aR,6aR,6bS,8aS,11R,12S,12aS,14aR,14bR)-8a-(Hydroxyméthyl)-4,4,6a,6b,11,12,14b-heptaméthyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydro-3-picénol

Urs-12-ene-3β,28-diol

Urs-12-ene-3b,28-diol

Uvaol

MFCD00009620

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China
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China
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China
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naturewill
China
Product Name: Uvaol
Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
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Delivery: Inquiry
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Uvaol

Use of Uvaol

Names

Uvaol Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Precursor & DownStream

Articles19

UvaolBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.