Nicotinohydrazide

Modify Date: 2024-01-02 09:51:09

Nicotinohydrazide structure	Common Name	Nicotinohydrazide
	CAS Number	553-53-7	Molecular Weight	137.139
	Density	1.2±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₆H₇N₃O	Melting Point	159-161 °C(lit.)
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of Nicotinohydrazide

Nicotinohydrazide (Nicotinic acid hydrazide) is a small molecular compound[1].

Name	Nicotinohydrazide
Synonym	More Synonyms

Description	Nicotinohydrazide (Nicotinic acid hydrazide) is a small molecular compound[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Kruszynski R. A structural and theoretical study of intermolecular interactions in nicotinohydrazide dihydrochloride. Acta Crystallogr C. 2011 Feb;67(Pt 2):o52-6.

Density	1.2±0.1 g/cm3
Melting Point	159-161 °C(lit.)
Molecular Formula	C₆H₇N₃O
Molecular Weight	137.139
Exact Mass	137.058914
PSA	68.01000
LogP	-0.83
Index of Refraction	1.584
Storage condition	2-8°C

Nicotinohydrazide MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QT1750000

CHEMICAL NAME :: Nicotinic acid, hydrazide

CAS REGISTRY NUMBER :: 553-53-7

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H7-N3-O

MOLECULAR WEIGHT :: 137.16

WISWESSER LINE NOTATION :: T6NJ CVMZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04178

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,691,1955 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 124 gm/kg/71W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :: ONCOBS Oncology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.21- 1967- Volume(issue)/page/year: 38,106,1981

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R40
Safety Phrases	S22-S26-S36/37/39
RIDADR	UN2811
WGK Germany	3
RTECS	QT1750000
Packaging Group	III
Hazard Class	6.1
HS Code	2933399090

Methyl nicotinate

CAS#:93-60-7

~98%

Nicotinohydrazide

CAS#:553-53-7

Literature: Khan, Khalid Mohammad; Rasheed, Maimona; Ullah, Zia; Hayat, Safdar; Kaukab, Farhana; Choudhary, M. Iqbal; Ur-Rahman, Atta; Perveen, Shahnaz Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 7 p. 1381 - 1387

Ethyl nicotinate

CAS#:614-18-6

~82%

Nicotinohydrazide

CAS#:553-53-7

Literature: Zou, Liang-Hua; Reball, Jens; Mottweiler, Jakob; Bolm, Carsten Chemical Communications (Cambridge, United Kingdom), 2012 , vol. 48, # 92 p. 11307 - 11309,3

Nicotinic acid

CAS#:59-67-6

~94%

Nicotinohydrazide

CAS#:553-53-7

Literature: Elshaarawy, Reda F.M.; Janiakb, Christoph Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2011 , vol. 66, # 12 p. 1202 - 1208

Nicotinamide

CAS#:98-92-0

~85%

Nicotinohydrazide

CAS#:553-53-7

Literature: Hassan, Heba A.; Abdel-Aziz, Mohamed; Abuo-Rahma, Gamal El-Din A.A.; Farag, Hassan H. Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 4 p. 1681 - 1692

Nicotinoyl chloride

CAS#:10400-19-8

Nicotinohydrazide

CAS#:553-53-7

Literature: Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 52, # 10 p. 1318 - 1324

N'-(1-((2S,4S)-...

CAS#:110925-43-4

Nicotinohydrazide

CAS#:553-53-7

Daunorubicin HCl

CAS#:23541-50-6

Literature: Pharmaceutical Chemistry Journal, , vol. 21, # 6 p. 398 - 402 Khimiko-Farmatsevticheskii Zhurnal, , vol. 21, # 6 p. 663 - 667

Precursor 6
CAS#:93-60-7 Methyl nicotinate CAS#:614-18-6 Ethyl nicotinate CAS#:59-67-6 Nicotinic acid CAS#:98-92-0 Nicotinamide
CAS#:10400-19-8 Nicotinoyl chloride CAS#:110925-43-4 N'-(1-((2S,4S)-...
DownStream 10
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CAS#:18960-15-1 3-Pyridinecarbo... CAS#:59-67-6 Nicotinic acid

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Controlled release studies of antimalarial 1, 3, 5-trisubstituted-2-pyrazolines from biocompatible chitosan-heparin Layer-by-Layer (LbL) self assembled thin films.

Colloids Surf. B Biointerfaces 125 , 151-9, (2015)

Herein we report the in-vitro controlled release properties of 1, 3, 5-trisubstituted-2-pyrazolines through Layer-by-Layer (LbL) self assembled thin films fabricated from chitosan and heparin sodium s...

Chemokine CCL17 induced by hypoxia promotes the proliferation of cervical cancer cell.

Am. J. Cancer Res. 5 , 3072-84, (2015)

Cervical cancer is often associated with hypoxia and many kinds of chemokines. But the relationship and role of hypoxia and Chemokine (C-C motif) ligand 17 (CCL17) in cervical cancer are still unknown...

Double-level "orthogonal" dynamic combinatorial libraries on transition metal template.

Proc. Natl. Acad. Sci. U. S. A. 98(4) , 1347-52, (2001)

Dynamic combinatorial libraries are mixtures of compounds that exist in a dynamic equilibrium and can be driven to compositional self adaptation via selective binding of a specific assembly of certain...

Nicotinohydrazide

pyridine-3-carbohydrazide

EINECS 209-041-0

MFCD00006383

3-Pyridinecarboxylic acid, hydrazide

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Nicotinohydrazide
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Nicotinohydrazide
Price: ￥438.0/100g ￥138.0/25g
Purity: 97.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Nicotinic hydrazide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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