Isobavachromene

Modify Date: 2024-01-06 15:42:46

Isobavachromene Structure
Isobavachromene structure
Common Name Isobavachromene
CAS Number 56083-03-5 Molecular Weight 322.354
Density 1.3±0.1 g/cm3 Boiling Point 535.1±50.0 °C at 760 mmHg
Molecular Formula C20H18O4 Melting Point 203-204℃
MSDS N/A Flash Point 193.7±23.6 °C

 Use of Isobavachromene


4-Hydroxylonchocarpin is a chalcone compound from an extract of Psoralea corylifolia. 4-Hydroxylonchocarpin increases phosphorylation of p38 MAPK, JNK and ERK. 4-Hydroxylonchocarpin has diverse pharmacological activities, including antibacterial, antifungal, anticancer, antireverse transcriptase, antitubercular, antimalarial, anti-inflammatory and antioxidant activities[1].

 Names

Name Isobavachromene
Synonym More Synonyms

 Isobavachromene Biological Activity

Description 4-Hydroxylonchocarpin is a chalcone compound from an extract of Psoralea corylifolia. 4-Hydroxylonchocarpin increases phosphorylation of p38 MAPK, JNK and ERK. 4-Hydroxylonchocarpin has diverse pharmacological activities, including antibacterial, antifungal, anticancer, antireverse transcriptase, antitubercular, antimalarial, anti-inflammatory and antioxidant activities[1].
Related Catalog
References

[1]. Lim J, et al. Antimelanogenic effect of 4-hydroxylonchocarpin through the inhibition of tyrosinase-related proteins and MAPK phosphatase. Exp Dermatol. 2016 Jul;25(7):574-6.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 535.1±50.0 °C at 760 mmHg
Melting Point 203-204℃
Molecular Formula C20H18O4
Molecular Weight 322.354
Flash Point 193.7±23.6 °C
Exact Mass 322.120514
PSA 66.76000
LogP 5.99
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.651
Storage condition 2-8℃

 Safety Information

Hazard Codes Xi

 Synonyms

(2E)-1-(5-hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one
(2E)-1-(5-Hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(4-hydroxyphenyl)-2-propen-1-one
2-Propen-1-one, 1-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-hydroxyphenyl)-, (2E)-
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