PIPES

Modify Date: 2024-01-02 11:14:57

PIPES Structure
PIPES structure
Common Name PIPES
CAS Number 5625-37-6 Molecular Weight 670.682
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C16H33N4Na3O12S4 Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point N/A

 Use of PIPES


PIPES (1,4-Piperazinediethanesulfonic acid) is an important component of PIPES buffer agent used in biochemistry[1].

 Names

Name 2,2'-piperazine-1,4-diylbisethanesulfonic acid
Synonym More Synonyms

 PIPES Biological Activity

Description PIPES (1,4-Piperazinediethanesulfonic acid) is an important component of PIPES buffer agent used in biochemistry[1].
Related Catalog
In Vitro To prepare the pH PIPES buffer, 173 g of 1,4-piperazinediethanesulfonic acid are dissolved into 1 L of deionized water. The pH of the PIPES buffer is adjusted to 6.8 by adding pellets of sodium hydroxide. PIPES buffer can be used to PIPES buffer, it can prevent the glutaraldehyde fixation induced lipid loss and artifacts[1].
References

[1]. Jason Moggridge, et al. Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics. Technol Cancer Res Treat. 2017 Dec;16(6):997-1005.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Melting Point >300 °C(lit.)
Molecular Formula C16H33N4Na3O12S4
Molecular Weight 670.682
Exact Mass 670.067078
PSA 131.98000
LogP -4.21
Index of Refraction 1.566
Storage condition Store at RT.
Water Solubility 0.1 M NaOH: 0.25 g/mL, clear, colorless

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 29335995

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles156

More Articles
Effect of (2)H and (18)O water isotopes in kinesin-1 gliding assay.

PeerJ 2 , e284, (2014)

We show for the first time the effects of heavy-hydrogen water ((2)H2O) and heavy-oxygen water (H2 (18)O) on the gliding speed of microtubules on kinesin-1 coated surfaces. Increased fractions of isot...

Evidence that TSC2 acts as a transcription factor and binds to and represses the promoter of Epiregulin.

Nucleic Acids Res. 42(10) , 6243-55, (2014)

The TSC2 gene, mutated in patients with tuberous sclerosis complex (TSC), encodes a 200 kDa protein TSC2 (tuberin). The importance of TSC2 in the regulation of cell growth and proliferation is irrefut...

Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination.

Cell. Mol. Life Sci. 71(24) , 4895-910, (2014)

Membrane proteins are key elements in cell physiology and drug targeting, but getting a high-resolution structure by crystallographic means is still enormously challenging. Novel strategies are in big...

 Synonyms

Sodium 2,2'-(1,4-piperazinediyl)diethanesulfonate 2-[4-(2-sulfoethyl)-1-piperazinyl]ethanesulfonate (3:1:1)
Piperazine-N,N'-bis (2-ethanesulfonic acid)
1,4-Piperazinediethanesulfonic acid, sodium salt (2:3)
PIPES
2,2'-Piperazine-1,4-diyldiethanesulfonic acid
2,2'-(1,4-Piperazinediyl)diethanesulfonic acid
1,4-Piperazine bis(ethanesulfonic acid)
1,4-Piperazinediethanesulfonic acid sesquisodium salt
Piperazine-N,N'-bis(2-ethanesulfonic acid)
Piperazine-N,N′-bis(2-ethanesulfonic acid)
Piperazine-1,4-bis(2-ethanesulfonic acid) sesquisodium salt
1,4-Piperazinediethanesulfonic acid
MFCD00006159
trisodium,2-[4-(2-sulfoethyl)piperazin-1-yl]ethanesulfonate,2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate
EINECS 227-057-6
2,2′-piperazine-1,4-diylbisethanesulfonic acid
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