Captopril EP Impurity D

Modify Date: 2024-01-02 17:32:22

Captopril EP Impurity D Structure
Captopril EP Impurity D structure
Common Name Captopril EP Impurity D
CAS Number 56970-78-6 Molecular Weight 167.00100
Density 1.625g/cm3 Boiling Point 230.5ºC at 760mmHg
Molecular Formula C4H7BrO2 Melting Point N/A
MSDS N/A Flash Point 93.2ºC

 Use of Captopril EP Impurity D


Captopril EP Impurity D is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3].

 Names

Name 3-bromo-2-methylpropionic acid
Synonym More Synonyms

 Captopril EP Impurity D Biological Activity

Description Captopril EP Impurity D is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3].
Related Catalog
References

[1]. ANCA GABRIELA CÂRJE, et al. HPLC-UV METHOD APPROACH FOR THE ANALYSIS AND IMPURITY PROFILING OF CAPTOPRIL.

[2]. Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64(11):2263-2268.

[3]. Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35.

 Chemical & Physical Properties

Density 1.625g/cm3
Boiling Point 230.5ºC at 760mmHg
Molecular Formula C4H7BrO2
Molecular Weight 167.00100
Flash Point 93.2ºC
Exact Mass 165.96300
PSA 37.30000
LogP 1.10200
Index of Refraction 1.453

 Safety Information

Hazard Codes C
RIDADR 3265
Packaging Group II
HS Code 2915900090

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Synonyms

methacrylic acid acid
3-BROMO-2-METHYL-PROPANOIC ACID
2-methyl 3-bromopropanoic acid
2-METHYL-3-BROMOPROPIONIC ACID
3-broMo-2-Methylbutanoate
3-BROMOISOBUTYRIC ACID
Methyl-3-bromopropionicacid
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