NSC 87877
Modify Date: 2025-08-23 12:24:51
NSC 87877 structure
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Common Name | NSC 87877 | ||
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| CAS Number | 56990-57-9 | Molecular Weight | 459.45 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C19H13N3O7S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NSC 87877NSC-87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively[1]. NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26)[2]. |
| Name | (7E)-8-oxo-7-[(6-sulfonaphthalen-2-yl)hydrazinylidene]quinoline-5-sulfonic acid |
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| Synonym | More Synonyms |
| Description | NSC-87877 is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (SH-PTP2 and SH-PTP1), with IC50 values of 0.318 μM, 0.355 μM shp2 and shp1, respectively[1]. NSC-87877 also inhibits dual-specificity phosphatase 26 (DUSP26)[2]. |
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| Related Catalog | |
| Target |
IC50: 0.318 μM (shp2), 0.355 μM (shp1)[1]. |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Molecular Formula | C19H13N3O7S2 |
| Molecular Weight | 459.45 |
| Exact Mass | 459.019501 |
| PSA | 183.34000 |
| LogP | 0.12 |
| Index of Refraction | 1.758 |
| 5-Quinolinesulfonic acid, 8-hydroxy-7-[(E)-2-(6-sulfo-2-naphthalenyl)diazenyl]- |
| 8-Hydroxy-7-[(E)-(6-sulfo-2-naphthyl)diazenyl]-5-quinolinesulfonic acid |
| 8-hydroxy-7-((6-sulfo-2-naphthyl)diazenyl)-5-quinolinesulfonic acid |
| 8-Hydroxy-7-[(E)-(6-sulfo-2-naphthyl)diazenyl]quinoline-5-sulfonic acid |
| 5-Quinolinesulfonic acid, 8-hydroxy-7-(6-sulfo-2-naphthylazo)- |
| 8-Hydroxy-7-(6-sulfo-naphthalen-2-ylazo)-quinoline-5-sulfonic acid |