Carboprost tromethamine
Modify Date: 2025-08-25 22:38:58
Carboprost tromethamine structure
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Common Name | Carboprost tromethamine | ||
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| CAS Number | 58551-69-2 | Molecular Weight | 489.643 | |
| Density | 1.153g/cm3 | Boiling Point | 536.6ºC at 760 mmHg | |
| Molecular Formula | C25H47NO8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 292.4ºC | |
Use of Carboprost tromethamineCarboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F2α. Carboprost tromethamine can effectively promote law contraction of the uterus and significantly reduce the amount of bleeding during and after delivery[1][2]. |
| Name | carboprost tromethamine |
|---|---|
| Synonym | More Synonyms |
| Description | Carboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F2α. Carboprost tromethamine can effectively promote law contraction of the uterus and significantly reduce the amount of bleeding during and after delivery[1][2]. |
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| Related Catalog | |
| In Vivo | Carboprost tromethamine has a significant effect on the prevention of postpartum hemorrhage in cesarean section, and has a significant effect on improving the state of hypercoagulable blood and maintaining the stable hemodynamic state. Carboprost tromethamine has been accounted for to be 84-96% successful in the treatment of persistent hemorrhage because of uterine atony[1]. |
| References |
| Density | 1.153g/cm3 |
|---|---|
| Boiling Point | 536.6ºC at 760 mmHg |
| Molecular Formula | C25H47NO8 |
| Molecular Weight | 489.643 |
| Flash Point | 292.4ºC |
| Exact Mass | 489.330170 |
| PSA | 184.70000 |
| LogP | 1.79410 |
| Water Solubility | Soluble in water. |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| RIDADR | NONH for all modes of transport |
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[The use of prostaglandin F2alpha (Prostin 15M) for terminationof second trimester pregnancy].
Akush. Ginekol. (Sofiia.) 52(2) , 53-5, (2013) The authors describe a case of terminating a second trimester pregnancy in 21 gestational weeks with use of Prostin 15 M. The patient come to the clinic in 21 gestational week with spontaneous rupture... |
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[Application of Pfizer drugs in the obstetrics and gynecology practice].
Akush. Ginekol. (Sofiia.) 48 Suppl 1 , 41-4, (2009)
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[Some possibilities for application of Pfizer medicines--Prostin 15m, Prostin E2, Prepidil gel, Dostinex, Synarel--in the obstetrician practice].
Akush. Ginekol. (Sofiia.) 46 Suppl 2 , 57-60, (2007) The authors make a clinical and pharmacological overview of the possibilities of application in the obstetrician practice of part of the medicines of the company Pfiser. Some of these medicines have n... |
| (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(3S)-3-hydroxy-3-methyl-1-octenyl)cyclopentyl)-5-heptenoic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) |
| (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid - 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1) |
| (15S)-15-Methylprostaglandin F2a Tromethamine |
| (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) |
| (5Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-3-methyloct-1-en-1-yl]cyclopentyl}hept-5-ensäure--2-amino-2-(hydroxymethyl)propan-1,3-diol(1:1) |
| Hemabate |
| Prostin/15M |
| acide (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-3-méthyloct-1-én-1-yl]cyclopentyl}hept-5-énoïque - 2-amino-2-(hydroxyméthyl)propane-1,3-diol (1:1) |
| Carboprost tromethamine salt |
| 15(S)15-Methyl pgf2a Tromethamine Salt |
| Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, (5Z,9α,11α,13E,15S)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1) |
| (5Z,9a,11a,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic Acid compd. with 2-Amino-2-(hydroxymethyl)-1,3-propanediol (1:1) |
| Carboprost trometamol |
| Carboprost tromethamine |
| U 32921E |
| (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-3-methyloct-1-en-1-yl]cyclopentyl}hept-5-enoic acid - 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1) |