Palifosfamide tromethamine
Modify Date: 2024-01-30 11:22:19
Palifosfamide tromethamine structure
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Common Name | Palifosfamide tromethamine | ||
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| CAS Number | 1070409-31-2 | Molecular Weight | 342.15700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H22Cl2N3O5P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Palifosfamide tromethaminePalifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic. |
| Name | 2-amino-2-(hydroxymethyl)propane-1,3-diol,bis(2-chloroethylamino)phosphinic acid |
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| Synonym | More Synonyms |
| Description | Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic. |
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| Related Catalog | |
| References |
| Molecular Formula | C8H22Cl2N3O5P |
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| Molecular Weight | 342.15700 |
| Exact Mass | 341.06700 |
| PSA | 157.88000 |
| ZIO-201-T |
| UNII-0X5A3C04ID |
| Palifosfamide tromethamine |