(D-Trp8)-Somatostatin-14 trifluoroacetate salt

Modify Date: 2024-01-07 08:46:53

(D-Trp8)-Somatostatin-14 trifluoroacetate salt Structure
(D-Trp8)-Somatostatin-14 trifluoroacetate salt structure
Common Name (D-Trp8)-Somatostatin-14 trifluoroacetate salt
CAS Number 58976-46-8 Molecular Weight 1637.878
Density 1.4±0.1 g/cm3 Boiling Point 1970.9±65.0 °C at 760 mmHg
Molecular Formula C76H104N18O19S2 Melting Point N/A
MSDS N/A Flash Point 1145.7±34.3 °C

 Use of (D-Trp8)-Somatostatin-14 trifluoroacetate salt


[D-Trp8] Somatostatin-14, a tetradecapeptide, is an analog of Somatostatin more potent than the native Somatostatin[1].

 Names

Name ala-gly-cys-lys-asn-phe-phe-d-trp-lys-thr-phe-thr-ser-cys
Synonym More Synonyms

  Biological Activity

Description [D-Trp8] Somatostatin-14, a tetradecapeptide, is an analog of Somatostatin more potent than the native Somatostatin[1].
Related Catalog
In Vitro [D-Trp8] Somatostatin-14 抑制生长激素、胰高血糖素和胰岛素释放的效力是 Somatostatin 的 6-8 倍[1]。
References

[1]. J Rivier, et al. D-Trp8-somatostatin: an analog of somatostatin more potent than the native molecule. Biochem Biophys Res Commun. 1975 Jul 22;65(2):746-51.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1970.9±65.0 °C at 760 mmHg
Molecular Formula C76H104N18O19S2
Molecular Weight 1637.878
Flash Point 1145.7±34.3 °C
Exact Mass 1636.716675
PSA 663.83000
LogP -4.25
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.670

 Synonyms

M.W. 686.90 C33H46N6O10
D-Ser2,Leu5,Thr6-enkephalin
Dislet
Dstle
TYR-D-SER-GLY-PHE-LEU-THR
L-Alanyl-N-[(4R,7S,10S,13S,16S,19S,22R,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide
L-tyrosyl-D-serylglycyl-L-phenylalanyl-L-leucyl-L-threonine
Glycinamide, L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22R,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-13,25,28-tris(phenylmethyl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacont-37-yl]-
2-Ser-Thr-Leu-enkephalin
(D-Trp8)-Somatostatin-14
[D-Trp8]-Somatostatin-14
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