11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID
Modify Date: 2024-01-19 12:18:59
11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID structure
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Common Name | 11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID | ||
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| CAS Number | 596104-94-8 | Molecular Weight | 318.450 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 493.2±24.0 °C at 760 mmHg | |
| Molecular Formula | C20H30O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 266.2±19.4 °C | |
Use of 11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACIDCAY10410 (11-Oxo-prosta-5Z), a 15d-PGJ2 analog, is a potent PPARγ agonist. CAY10410 has the ability to activate PPARγ in human B cells without killing B lymphocytes[1]. |
| Name | 7-(2-oct-2-enylidene-3-oxocyclopentyl)hept-5-enoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | CAY10410 (11-Oxo-prosta-5Z), a 15d-PGJ2 analog, is a potent PPARγ agonist. CAY10410 has the ability to activate PPARγ in human B cells without killing B lymphocytes[1]. |
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| Related Catalog | |
| Target |
PPARγ |
| In Vitro | Cay10410 (11-Oxo-prosta-5Z; 1 μM; 24 h) 激活 PPRE-LUC 活性，该激活被 B细胞中的 PPARγ DN 抑制[1]。 Cay10410 (0-25 μM; 48 h) 对 Ramos 细胞或正常人 B 细胞均无抑制作用，即使剂量高达 25 μM[1]。 |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 493.2±24.0 °C at 760 mmHg |
| Molecular Formula | C20H30O3 |
| Molecular Weight | 318.450 |
| Flash Point | 266.2±19.4 °C |
| Exact Mass | 318.219482 |
| PSA | 54.37000 |
| LogP | 4.84 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.546 |
| Storage condition | -20℃ |
| (5Z,12E,14Z)-11-Oxoprosta-5,12,14-trien-1-oic acid |
| Prosta-5,12,14-trien-1-oic acid, 11-oxo-, (5Z,12E,14Z)- |