DCEBIO
Modify Date: 2025-08-26 19:57:04
DCEBIO structure
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Common Name | DCEBIO | ||
|---|---|---|---|---|
| CAS Number | 60563-36-2 | Molecular Weight | 231.08 | |
| Density | 1.413g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C9H8Cl2N2O | Melting Point | 209.5-210.5 °C | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of DCEBIODCEBIO, a derivative of 1-EBIO, is an extremely potent activator of Cl－ secretion in T84 colonic cells[1]. DCEBIO stimulates Cl－ secretion via the activation of hIK1 K＋ channels and the activation of an apical membrane Cl－ conductance[2]. |
| Name | 5,6-dichloro-3-ethyl-1H-benzimidazol-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | DCEBIO, a derivative of 1-EBIO, is an extremely potent activator of Cl－ secretion in T84 colonic cells[1]. DCEBIO stimulates Cl－ secretion via the activation of hIK1 K＋ channels and the activation of an apical membrane Cl－ conductance[2]. |
|---|---|
| Related Catalog | |
| Target |
Cl－ secretion[1] |
| References |
| Density | 1.413g/cm3 |
|---|---|
| Melting Point | 209.5-210.5 °C |
| Molecular Formula | C9H8Cl2N2O |
| Molecular Weight | 231.08 |
| Exact Mass | 230.00100 |
| PSA | 37.79000 |
| LogP | 2.65630 |
| Index of Refraction | 1.592 |
| InChIKey | LKHRMULASXZCLG-UHFFFAOYSA-N |
| SMILES | CCn1c(=O)[nH]c2cc(Cl)c(Cl)cc21 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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The Inhibition by Oxaliplatin, a Platinum-Based Anti-Neoplastic Agent, of the Activity of Intermediate-Conductance Ca²⁺-Activated K⁺ Channels in Human Glioma Cells.
Cell Physiol. Biochem. 37 , 1390-406, (2015) Oxaliplatin (OXAL) is a third-generation organoplatinum which is effective against advanced cancer cells including glioma cells. How this agent and other related compounds interacts with ion channels ... |
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Secondhand smoke inhibits both Cl- and K+ conductances in normal human bronchial epithelial cells.
Respir. Res. 10 , 120, (2009) Secondhand smoke (SHS) exposure is an independent risk factor for asthma, rhinosinusitis, and more severe respiratory tract infections in children and adults. Impaired mucociliary clearance with subse... |
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Name: qHTS to identify inhibitors of the New Delhi Metallo-beta-lactamase (NDM): assay vali...
Source: NCGC
External Id: adst_MBL_Abs_LOPAC_o1
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Name: Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro...
Source: NCGC
Target: N/A
External Id: SERCaMPGLuc-p1-antagonist
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|
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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|
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
Source: ChEMBL
Target: N/A
External Id: CHEMBL1266185
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
|
|
Name: qHTS Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2...
Source: NCGC
Target: ubiquitin carboxyl-terminal hydrolase 2 isoform a [Homo sapiens]
External Id: UBCH001
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
|
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Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
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| 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazole-2-one |
| 5,6-dichloro-1-ethyl-1,3-dihydro-benzoimidazol-2-one |
| DC-EBIO |
| 5,6-dichloro-3-ethyl benzimidazolone |
| 5,6-Dichlor-1-ethyl-benzimidazolon |
| 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one |
| 5,6-dichloro-1-ethyl-benzimidazolinone |
| Tocris-1422 |
| 5,6-Dichlor-2-oxo-1-ethyl-benzimidazolin |
| dichloro-EBIO |