Ethylpyruvate

Modify Date: 2024-01-02 13:48:44

Ethylpyruvate Structure
Ethylpyruvate structure
Common Name Ethylpyruvate
CAS Number 617-35-6 Molecular Weight 116.115
Density 1.0±0.1 g/cm3 Boiling Point 155.0±0.0 °C at 760 mmHg
Molecular Formula C5H8O3 Melting Point -58 °C
MSDS Chinese USA Flash Point 45 ºC
Symbol GHS02
GHS02
Signal Word Warning

 Use of Ethylpyruvate


Ethyl pyruvate is a simple derivative of the endogenous metabolite, pyruvic acid. Ethyl pyruvate is an anti-inflammatory agent[1].

 Names

Name Ethyl pyruvate
Synonym More Synonyms

 Ethylpyruvate Biological Activity

Description Ethyl pyruvate is a simple derivative of the endogenous metabolite, pyruvic acid. Ethyl pyruvate is an anti-inflammatory agent[1].
Related Catalog
References

[1]. Fink MP. Ethyl pyruvate: a novel anti-inflammatory agent. J Intern Med. 2007 Apr;261(4):349-62.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 155.0±0.0 °C at 760 mmHg
Melting Point -58 °C
Molecular Formula C5H8O3
Molecular Weight 116.115
Flash Point 45 ºC
Exact Mass 116.047340
PSA 43.37000
LogP 0.05
Vapour Pressure 3.1±0.2 mmHg at 25°C
Index of Refraction 1.399
Storage condition 0-6°C

 Safety Information

Symbol GHS02
GHS02
Signal Word Warning
Hazard Statements H226
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi,F
Risk Phrases R10
Safety Phrases S16
RIDADR UN 3272 3/PG 3
WGK Germany 3
Packaging Group III
Hazard Class 3
HS Code 2918300090

 Synthetic Route

 Customs

HS Code 2918300090
Summary 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles46

More Articles
Effects of ethyl pyruvate on leukocyte-endothelial interactions in the mesenteric microcirculation during early sepsis treatment.

Clinics (Sao. Paulo.) 70 , 508-14, (2015)

Experimental studies on sepsis have demonstrated that ethyl pyruvate is endowed with antioxidant and anti-inflammatory properties. This study aimed to investigate the effects of ethyl pyruvate on leuk...

HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells.

Cancer Res. 74(20) , 5723-33, (2014)

Chronic inflammation often precedes malignant transformation and later drives tumor progression. Likewise, subversion of the immune system plays a role in tumor progression, with tumoral immune escape...

Ethyl pyruvate significantly inhibits tumour necrosis factor-α, interleukin-1β and high mobility group box 1 releasing and attenuates sodium taurocholate-induced severe acute pancreatitis associated with acute lung injury.

Clin. Exp. Immunol. 172(3) , 417-26, (2013)

In this study, we examined the effect of ethyl pyruvate (EP) on pulmonary inflammation in rats with severe pancreatitis-associated acute lung injury (ALI). Severe acute pancreatitis (SAP) was induced ...

 Synonyms

MFCD00009123
ethyl 2-oxopropanoate
EINECS 210-511-2
Ethylpyruvate
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