Sapropterin

Modify Date: 2024-01-11 19:52:23

Sapropterin Structure
Sapropterin structure
Common Name Sapropterin
CAS Number 62989-33-7 Molecular Weight 241.247
Density 1.9±0.1 g/cm3 Boiling Point 506.6±60.0 °C at 760 mmHg
Molecular Formula C9H15N5O3 Melting Point N/A
MSDS N/A Flash Point 260.2±32.9 °C

 Use of Sapropterin


Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin can be used in study of phenylketonuria (PKU)[1].

 Names

Name (6r,s)-5,6,7,8-tetrahydro-l-biopterin
Synonym More Synonyms

 Sapropterin Biological Activity

Description Sapropterin ((6R)-BH4) is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin can be used in study of phenylketonuria (PKU)[1].
Related Catalog

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 506.6±60.0 °C at 760 mmHg
Molecular Formula C9H15N5O3
Molecular Weight 241.247
Flash Point 260.2±32.9 °C
Exact Mass 241.117493
PSA 136.29000
LogP -4.22
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.822
Storage condition −20°C

 Safety Information

Hazard Codes Xn
Risk Phrases R22
WGK Germany 3
RTECS UO3516500
HS Code 2933990090

 Synthetic Route

~81%

Sapropterin Structure

Sapropterin

CAS#:62989-33-7

Literature: Matsuura, Sadao; Murata, Shizuaki; Sugimoto, Takashi Heterocycles, 1985 , vol. 23, # 12 p. 3115 - 3120

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Sapropterin Structure

Sapropterin

CAS#:62989-33-7

Literature: Matsuura, Sadao; Murata, Shizuaki; Sugimoto, Takashi Tetrahedron Letters, 1986 , vol. 27, # 5 p. 585 - 588

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Sapropterin
(6R,1'R,2'S)-6-(1',2'-dihydroxypropyl)-5,6,7,8-tetrahydrobiopterin
6b-5,6,7,8-Tetrahydro-L-biopterin
Dapropterin
(6R)-2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-4(1H)-pteridinone
(6R)-5,6,7,8-tetrahydro-L-biopterin
(6R)-Tetrahydrobiopterin
6R-tetahydrobiopterin
6R-Tetrahydro-L-biopterin
R-THBP6R-BH4
(6R)-L-erythro-5,6,7,8-Tetrahydrobiopterin
sapropterina
sapropterinum
(6R)-2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(1H)-one
R-THBP
(6R)-5,6,7,8-Tetrahydrobiopterin
(6R)-L-erythro-Tetrahydrobiopterin
4(1H)-Pteridinone, 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-, (6R)-
[6R-[6R*(1R*,2S*)]]-2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone
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