2-Thiazolamine,4,5-diphenyl

Modify Date: 2026-07-06 17:18:59

2-Thiazolamine,4,5-diphenyl Structure
2-Thiazolamine,4,5-diphenyl structure
Common Name 2-Thiazolamine,4,5-diphenyl
CAS Number 6318-74-7 Molecular Weight 252.33400
Density 1.23 g/cm3 Boiling Point 420ºC at 760 mmHg
Molecular Formula C15H12N2S Melting Point N/A
MSDS USA Flash Point 207.8ºC

 Names

Name 4,5-diphenyl-1,3-thiazol-2-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.23 g/cm3
Boiling Point 420ºC at 760 mmHg
Molecular Formula C15H12N2S
Molecular Weight 252.33400
Flash Point 207.8ºC
Exact Mass 252.07200
PSA 67.15000
LogP 4.64050
InChIKey XDWGEGZDMFHZBL-UHFFFAOYSA-N
SMILES Nc1nc(-c2ccccc2)c(-c2ccccc2)s1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ2450000
CHEMICAL NAME :
Thiazole, 2-amino-4,5-diphenyl-
CAS REGISTRY NUMBER :
6318-74-7
BEILSTEIN REFERENCE NO. :
0194032
LAST UPDATED :
199706
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C15-H12-N2-S
MOLECULAR WEIGHT :
252.35
WISWESSER LINE NOTATION :
T5N CSJ BZ DR& ER

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

 Safety Information

Hazard Codes Xi
HS Code 2934100090

 Synthetic Route

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 2-Thiazolamine,4,5-diphenylBioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
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 Synonyms

diphenyl-1,3-thiazol-2-amine
2-Thiazolamine,4,5-diphenyl
4,5-diphenylthiazole-2-amine
Thiazole,2-amino-4,5-diphenyl
4,5-diphenylthiazol-2-amine
4,5-Diphenyl-2-thiazolamine,monohydrochloride
4,5-Diphenyl-thiazol-2-ylamine
4,5-diphenyl-2-aminothiazole
4,5-Diphenyl-thiazol-2-ylamin
2-amino-4,5-diphenylthiazole
Bax 439
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