Val-Cit-PAB-MMAE

Modify Date: 2024-01-02 11:17:38

Val-Cit-PAB-MMAE Structure
Val-Cit-PAB-MMAE structure
Common Name Val-Cit-PAB-MMAE
CAS Number 644981-35-1 Molecular Weight 1123.427
Density 1.2±0.1 g/cm3 Boiling Point 1211.9±65.0 °C at 760 mmHg
Molecular Formula C58H94N10O12 Melting Point N/A
MSDS N/A Flash Point 686.7±34.3 °C

 Use of Val-Cit-PAB-MMAE


Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the peptide Val-Cit-PAB.

 Names

Name Val-Cit-PAB-MMAE
Synonym More Synonyms

 Val-Cit-PAB-MMAE Biological Activity

Description Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the peptide Val-Cit-PAB.
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 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 1211.9±65.0 °C at 760 mmHg
Molecular Formula C58H94N10O12
Molecular Weight 1123.427
Flash Point 686.7±34.3 °C
Exact Mass 1122.705322
LogP 4.80
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.552
Storage condition 2-8℃

 Synonyms

L-Ornithinamide, L-valyl-N-(aminocarbonyl)-N-[4-[(5S,8S,11S,12R)-12-[2-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-oxoethy l]-4,10-dimethyl-5,8-bis(1-methylethyl)-11-[(1S)-1-methylpropyl]-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl]-
L-Valyl-N-{4-[(5S,8S,11S,12R)-11-[(2S)-2-butanyl]-12-(2-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenyl-2-propanyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-2-oxoethyl)-5,8-diisopropyl-4, ;10-dimethyl-3,6,9-trioxo-2,13-dioxa-4,7,10-triazatetradec-1-yl]phenyl}-N-carbamoyl-L-ornithinamide
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Price: $1780/10mM*1mLinDMSO

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