5-Nitro-2-furancarboxylic Acid

Modify Date: 2024-01-13 15:01:05

5-Nitro-2-furancarboxylic Acid Structure
5-Nitro-2-furancarboxylic Acid structure
Common Name 5-Nitro-2-furancarboxylic Acid
CAS Number 645-12-5 Molecular Weight 157.08100
Density 1.72 g/cm3 (-53 C) Boiling Point 332ºC
Molecular Formula C5H3NO5 Melting Point 185-189 °C(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 5-Nitro-2-furoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.72 g/cm3 (-53 C)
Boiling Point 332ºC
Melting Point 185-189 °C(lit.)
Molecular Formula C5H3NO5
Molecular Weight 157.08100
Exact Mass 157.00100
PSA 96.26000
LogP 1.40920
Storage condition -20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LV2012000
CHEMICAL NAME :
2-Furoic acid, 5-nitro-
CAS REGISTRY NUMBER :
645-12-5
BEILSTEIN REFERENCE NO. :
0139373
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C5-H3-N-O5
MOLECULAR WEIGHT :
157.09
WISWESSER LINE NOTATION :
T5OJ BVQ ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Phage inhibition capacity
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
1 gm/L
REFERENCE :
VIRLAX Virology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1955- Volume(issue)/page/year: 99,257,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6649 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R36/37/38;R68
Safety Phrases S37/39-S36/37
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS LV2012000

 Synthetic Route

 Articles4

More Articles
5-Nitro-2-furoic acid hydrazones: design, synthesis and in vitro antimycobacterial evaluation against log and starved phase cultures.

Bioorg. Med. Chem. Lett. 20 , 4313-6, (2010)

Various 5-nitro-2-furoic acid hydrazones were synthesized and evaluated for in vitro activities against log and starved phase culture of two mycobacterial species and Mycobacterium tuberculosis (MTB) ...

Formation of methemoglobin by photoactivation of nitrofurantoin or of 5-nitrofurfural in rats exposed to UV-A light.

Toxicology 51(2-3) , 255-66, (1988)

The antibacterial drug nitrofurantoin (NFT) is notorious for causing hemolytic anemia, which may be related to the methemoglobinemia, another side-effect of NFT. As NFT is photolabile, and nitrite, we...

Synthesis of some new [1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and [1,2,4]triazolo[3,4-b][1,3,4] thiadiazoles starting from 5-nitro-2-furoic acid and evaluation of their antimicrobial activity.

Bioorg. Med. Chem. 19 , 4506-12, (2011)

New series of fused 1,2,4-triazoles such as, 6-(aryl)-3-(5-nitrofuran-2-yl)-5,6-dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles 4-8, 6-(alkyl/aryl amino)-3-(5-nitrofuran-2-yl)-[1,2,4]triazolo[3,4-b]...

 Synonyms

MFCD00003240
5-nitrofuran-2-carboxylic acid
EINECS 211-432-6