Furan-2-carboxylic acid

Modify Date: 2026-07-20 17:39:46

Furan-2-carboxylic acid Structure
Furan-2-carboxylic acid structure
 Common Name Furan-2-carboxylic acid
CAS Number 88-14-2 Molecular Weight 112.084
Density 1.3±0.1 g/cm3 Boiling Point 230-232 ºC
Molecular Formula C5H4O3 Melting Point 129-133 ºC
MSDS Chinese USA Flash Point 137 ºC
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Furan-2-carboxylic acid


2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[1]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[2].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2-furoic acid
Synonym More Synonyms

 Furan-2-carboxylic acid Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[1]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[2].
Related Catalog
In Vivo 2-Furoic acid significantly reduces serum cholesterol and serum triglyceride levels[2]. 2-Furoic acid also lowers the liver and small intestine ATP dependent citrate lyase, acetyl CoA synthetase, acyl CoA cholesterol acyl transferase, sn-glycerol 3-phosphate acyl transferase, phosphatidylate phosphohydrolase and heparin induced lipoprotein lipase activities[2]. 2-Furoic acid shows the LD50 of 250 mg/kg i.p. in the acute toxicity studies in mice[2].
References

[1]. Wordofa GG, et al. Tolerance and metabolic response of Pseudomonas taiwanensis VLB120 towards biomass hydrolysate-derived inhibitors. Biotechnol Biofuels. 2018 Jul 19;11:199.

[2]. Hall IH, et al. The hypolipidemic effects of 2-furoic acid in Sprague-Dawley rats. Arch Pharm (Weinheim). 1993 Jan;326(1):15-23.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.3±0.1 g/cm3
Boiling Point 230-232 ºC
Melting Point 129-133 ºC
Molecular Formula C5H4O3
Molecular Weight 112.084
Flash Point 137 ºC
Exact Mass 112.016045
PSA 50.44000
LogP 0.64
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.513
InChIKey SMNDYUVBFMFKNZ-UHFFFAOYSA-N
SMILES O=C(O)c1ccco1
Water Solubility 36 g/L (20 ºC)

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LV1763000
CHEMICAL NAME :
2-Furoic acid
CAS REGISTRY NUMBER :
88-14-2
BEILSTEIN REFERENCE NO. :
0110149
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C5-H4-O3
MOLECULAR WEIGHT :
112.09
WISWESSER LINE NOTATION :
T5OJ BVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
10 ug/plate
REFERENCE :
JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 1,15,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1977 No. of Facilities: 6 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 774 (estimated) No. of Female Employees: 10 (estimated)

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes C;Xi
Risk Phrases R34;R36/37/38
Safety Phrases S26-S36/37/39-S45-S36
RIDADR UN 3265 8/PG 2
WGK Germany 3
RTECS LV1763000
HS Code 29321900

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2932190090
Summary 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Articles38

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.

Clin. Chem. 40(6) , 862-6, (1994)

Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...

Optimization and Kinetic Studies on Biodiesel Production from Kusum (Schleichera triguga) Oil Using Response Surface Methodology.

J. Oleo Sci. 64 , 987-97, (2015)

In the present study, the low-cost non-edible kusum (Schleichera triguga) oil with a substantial amount of free fatty acid (FFA) was utilized for biodiesel synthesis. In pretreatment step, FFA was red...

High tolerance and physiological mechanism of Zymomonas mobilis to phenolic inhibitors in ethanol fermentation of corncob residue.

Biotechnol. Bioeng. 112 , 1770-82, (2015)

Corncob residue as the lignocellulosic biomass accumulated phenolic compounds generated from xylitol production industry. For utilization of this biomass, Zymomonas mobilis ZM4 was tested as the ethan...

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

2-furanyl-carboxylic acid
pyromucic acid
Furan-2-carboxylic acid
2-FURANCARBONYL CHLORIDE
2-Furoic acid
a-Furoicacid
Kyselina 2-furoova
2- FUROIC ACID
2-FUROIC ACID/FURAN-2-CARBOXYLIC ACID
Furoica
2-FURANCARBOXYLICACID
α-Furoic acid
EINECS 208-422-9
2-Furanoic acid
2-Furancarboxylic acid
MFCD00003228
2-furan-carboxylic acid
a-Furoic Acid

 Furan-2-carboxylic acid | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the boiling point of 2-furoic acid?
A: Boiling point of 2-furoic acid is 230-232 ºC.
Q: What are the uses of 2-furoic acid?
A: Main uses of 2-furoic acid: 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation[1]. 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats[2].
Q: What is the English name of 2-furoic acid?
A: The English name of 2-furoic acid is 2-furoic acid.
Q: What English synonyms does 2-furoic acid have?
A: English synonyms of 2-furoic acid: 2-furanyl-carboxylic acid, pyromucic acid, Furan-2-carboxylic acid, 2-FURANCARBONYL CHLORIDE, 2-Furoic acid, a-Furoicacid, Kyselina 2-furoova, 2- FUROIC ACID, 2-FUROIC ACID/FURAN-2-CARBOXYLIC ACID, Furoica, 2-FURANCARBOXYLICACID, α-Furoic acid, EINECS 208-422-9, 2-Furanoic acid, 2-Furancarboxylic acid, MFCD00003228, 2-furan-carboxylic acid, a-Furoic Acid.
Q: What are the upstream materials of 2-furoic acid?
A: Related upstream materials(CAS) of 2-furoic acid: 98-00-0;552-86-3;98-01-1;584-12-3;201230-82-2;110-00-9;124-38-9;611-13-2;2434-03-9;1192-62-7.
Q: What is the CAS number of 2-furoic acid?
A: CAS number of 2-furoic acid is 88-14-2.
Q: What is the InChIKey of 2-furoic acid?
A: InChIKey of 2-furoic acid is SMNDYUVBFMFKNZ-UHFFFAOYSA-N.
Q: What is the SMILES notation of 2-furoic acid?
A: SMILES notation of 2-furoic acid is O=C(O)c1ccco1.
Q: What are the downstream products of 2-furoic acid?
A: Related downstream products(CAS) of 2-furoic acid: 109930-25-8;380889-69-0;1917-15-3;4412-96-8;40172-95-0;31350-27-3;4412-91-3;54829-48-0;615-10-1;41019-43-6.
Q: What is the LogP of 2-furoic acid?
A: LogP of 2-furoic acid is 0.64.

 Furan-2-carboxylic acidfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
BioBioPha
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
Zhongshan Xingrui Chemical Co. , Ltd.
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