Levalbuterol tartrate

Modify Date: 2024-01-08 12:35:11

Levalbuterol tartrate Structure
Levalbuterol tartrate structure
Common Name Levalbuterol tartrate
CAS Number 661464-94-4 Molecular Weight 628.71
Density N/A Boiling Point N/A
Molecular Formula C30H48N2O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Levalbuterol tartrate


Levosalbutamol tartrate(levalbuterol) is the R-enantiomer of the short-acting β2-adrenergic receptor agonist salbutamol. IC50 Value:Target: β2-adrenergic receptorLevosalbutamol and salbutamol produced significantly better bronchodilator responses than placebo. Both the drugs showed equivalent time-dependent bronchodilator responses as measured by area under curve for percent change in FEV(1) and FVC over 6h. The time to onset of action, mean maximum bronchodilator response and duration of bronchodilator response were similar between levosalbutamol and salbutamol [1].

 Names

Name 4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol,(2R,3R)-2,3-dihydroxybutanedioic acid
Synonym More Synonyms

 Levalbuterol tartrate Biological Activity

Description Levosalbutamol tartrate(levalbuterol) is the R-enantiomer of the short-acting β2-adrenergic receptor agonist salbutamol. IC50 Value:Target: β2-adrenergic receptorLevosalbutamol and salbutamol produced significantly better bronchodilator responses than placebo. Both the drugs showed equivalent time-dependent bronchodilator responses as measured by area under curve for percent change in FEV(1) and FVC over 6h. The time to onset of action, mean maximum bronchodilator response and duration of bronchodilator response were similar between levosalbutamol and salbutamol [1].
Related Catalog
References

[1]. Jantikar A, et al. Comparison of bronchodilator responses of levosalbutamol and salbutamol given via a pressurized metered dose inhaler: a randomized, double blind, single-dose, crossover study. Respir Med. 2007 Apr;101(4):845-9.

 Chemical & Physical Properties

Molecular Formula C30H48N2O12
Molecular Weight 628.71
PSA 187.78000
Storage condition 2-8℃

 Synonyms

Levalbuterol tartrate
Xopenex HFA
(2R,3R)-2,3-Dihydroxysuccinic acid - 2-(hydroxymethyl)-4-{(1R)-1-hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}phenol (1:2)
Butanedioic acid, 2,3-dihydroxy-, (2R,3R)-, compd. with (αR)-α-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol (1:2)