SM-324405
Modify Date: 2024-01-31 16:27:13
SM-324405 structure
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Common Name | SM-324405 | ||
|---|---|---|---|---|
| CAS Number | 677773-91-0 | Molecular Weight | 385.42 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 654.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C19H23N5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 349.3±34.3 °C | |
Use of SM-324405SM-324405 is a TLR7 agonist, with pEC50 values of 7.3 and 6.6 for human TLR7 and Rat TLR7, respectively[1]. |
| Name | SM 324405 |
|---|---|
| Synonym | More Synonyms |
| Description | SM-324405 is a TLR7 agonist, with pEC50 values of 7.3 and 6.6 for human TLR7 and Rat TLR7, respectively[1]. |
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| Related Catalog | |
| In Vitro | SM-324405 is a novel candidate for immunotherapy of allergic diseases[1]. |
| In Vivo | SM-324405 (9e, intratracheal administration) effectively inhibits allergen-induced airway inflammation without inducing cytokines systemically[1]. SM-324405 exhibits t1/2 of 2.6 min in human plasma[2]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 654.0±65.0 °C at 760 mmHg |
| Molecular Formula | C19H23N5O4 |
| Molecular Weight | 385.42 |
| Flash Point | 349.3±34.3 °C |
| Exact Mass | 385.175018 |
| LogP | 1.55 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.645 |
| Methyl {3-[(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)methyl]phenyl}acetate |
| MFCD30182295 |
| Benzeneacetic acid, 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]-, methyl ester |