1,4-BIS(TRICHLOROMETHYL)BENZENE

Modify Date: 2024-01-06 00:28:20

1,4-BIS(TRICHLOROMETHYL)BENZENE Structure
1,4-BIS(TRICHLOROMETHYL)BENZENE structure
 Common Name 1,4-BIS(TRICHLOROMETHYL)BENZENE
CAS Number 68-36-0 Molecular Weight 312.83500
Density 1.628 g/cm3 Boiling Point 312 °C
Molecular Formula C8H4Cl6 Melting Point 106-110 °C
MSDS N/A Flash Point 153ºC

 Use of 1,4-BIS(TRICHLOROMETHYL)BENZENE


Hexachloroparaxylene could be used in the study of in fascioliasis in swine[1].

 Names

Name 1,4-Bis(trichloromethyl)benzene
Synonym More Synonyms

 1,4-BIS(TRICHLOROMETHYL)BENZENE Biological Activity

Description Hexachloroparaxylene could be used in the study of in fascioliasis in swine[1].
Related Catalog
References

[1]. A D Kabaloev, et al. Hexachloroparaxylene in fascioliasis in swine. Veterinariia. 1968 May;45(5):47.  

 Chemical & Physical Properties

Density 1.628 g/cm3
Boiling Point 312 °C
Melting Point 106-110 °C
Molecular Formula C8H4Cl6
Molecular Weight 312.83500
Flash Point 153ºC
Exact Mass 309.84400
LogP 5.34000
Index of Refraction 1.584

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZE4655000
CHEMICAL NAME :
p-Xylene, alpha,alpha,alpha,alpha',alpha',alpha'-hexachloro-
CAS REGISTRY NUMBER :
68-36-0
BEILSTEIN REFERENCE NO. :
2051282
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C8-H4-Cl6
MOLECULAR WEIGHT :
312.82
WISWESSER LINE NOTATION :
GXGGR DXGGG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 21,34,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 mg/kg/10D-I
TOXIC EFFECTS :
Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
REFERENCE :
ZHYGAM Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1955- Volume(issue)/page/year: 32,107,1986 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2330 mg/kg
SEX/DURATION :
male 26 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
REFERENCE :
GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 21,34,1982
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2330 mg/kg
SEX/DURATION :
female 26 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967- Volume(issue)/page/year: 21,34,1982 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 10 mg/m3;Skin JAN 1993

 Safety Information

Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S45-S36/37/39-S26
RTECS ZE4655000
HS Code 2903999090

 Synthetic Route

p-Xylene structure

p-Xylene

CAS#:106-42-3

~%

1,4-BIS(TRICHLOROMETHYL)BENZENE Structure

1,4-BIS(TRICHLO...

CAS#:68-36-0
Literature: US2654789 , ; Industrial and Engineering Chemistry, , vol. 39, p. 302 US2132361 , ; Industrial and Engineering Chemistry, , vol. 39, p. 298 FR798727 ;
4-Methylbenzyl chloride structure

4-Methylbenzyl ...

CAS#:104-82-5

~%

1,4-BIS(TRICHLOROMETHYL)BENZENE Structure

1,4-BIS(TRICHLO...

CAS#:68-36-0
Literature: Nation. Nuclear Energy Ser., Abt. VII 1 <1951> 207, 216-218
Formaldehyde structure

Formaldehyde

CAS#:50-00-0
Toluene structure

Toluene

CAS#:108-88-3

~%

1,4-BIS(TRICHLOROMETHYL)BENZENE Structure

1,4-BIS(TRICHLO...

CAS#:68-36-0

1-(Dichloromethyl)-2-(trichloromethyl)benzene structure

1-(Dichlorometh...

CAS#:2741-57-3
Literature: Faserforsch. Textiltech., , vol. 4, p. 464,465
1,4-Bis(trifluoromethyl)benzene structure

1,4-Bis(trifluo...

CAS#:433-19-2

~%

1,4-BIS(TRICHLOROMETHYL)BENZENE Structure

1,4-BIS(TRICHLO...

CAS#:68-36-0
Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 37, # 7 p. 1626 - 1631,1544 - 1547
Formaldehyde structure

Formaldehyde

CAS#:50-00-0
Toluene structure

Toluene

CAS#:108-88-3

~%

1,4-BIS(TRICHLOROMETHYL)BENZENE Structure

1,4-BIS(TRICHLO...

CAS#:68-36-0
Literature: Faserforsch. Textiltech., , vol. 4, p. 464,465
p-Xylene structure

p-Xylene

CAS#:106-42-3
Chlorine structure

Chlorine

CAS#:7782-50-5

~%

1,4-BIS(TRICHLOROMETHYL)BENZENE Structure

1,4-BIS(TRICHLO...

CAS#:68-36-0
Literature: US2132361 , ; FR798727 , ;

 Customs

HS Code 2903999090
Summary 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

EINECS 200-686-3
MFCD00000791
1,4-bis(trichloromethyl)benzene
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