N6-Etheno 2'-deoxyadenosine
N6-Etheno 2'-deoxyadenosine structure
|
Common Name | N6-Etheno 2'-deoxyadenosine | ||
|---|---|---|---|---|
| CAS Number | 68498-25-9 | Molecular Weight | 275.26300 | |
| Density | 1.85 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C12H13N5O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of N6-Etheno 2'-deoxyadenosineN6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues[1]. |
| Name | Etheno-2'-deoxy-β-D-adenosine |
|---|---|
| Synonym | More Synonyms |
| Description | N6-Etheno 2'-deoxyadenosine is a reactive oxygen species (ROS)/reactive nitrogen species (RNS)-induced DNA oxidation product, used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.85 g/cm3 |
|---|---|
| Molecular Formula | C12H13N5O3 |
| Molecular Weight | 275.26300 |
| Exact Mass | 275.10200 |
| PSA | 97.70000 |
| Index of Refraction | 1.876 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
|
~90%
N6-Etheno 2'-de... CAS#:68498-25-9 |
| Literature: Chirakul; Litzer; Sigurdsson Nucleosides, Nucleotides and Nucleic Acids, 2001 , vol. 20, # 12 p. 1903 - 1913 |
|
~%
N6-Etheno 2'-de... CAS#:68498-25-9 |
| Literature: Journal of the American Chemical Society, , vol. 117, # 43 p. 10781 - 10782 |
|
~%
N6-Etheno 2'-de... CAS#:68498-25-9 |
| Literature: Environmental Toxicology, , vol. 22, # 2 p. 222 - 227 |
|
~%
N6-Etheno 2'-de... CAS#:68498-25-9 |
| Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 20, # 12 p. 1903 - 1913 |
|
~96%
N6-Etheno 2'-de... CAS#:68498-25-9 |
| Literature: Mueller, Michael; Hutchinson, Linda K.; Peter Guengerich Chemical Research in Toxicology, 1996 , vol. 9, # 7 p. 1140 - 1144 |
| Precursor 7 | |
|---|---|
| DownStream 3 | |
![7H-Imidazo[4,5-d]-1,2,3-triazin-4-amine,7-(2-deoxy-b-D-erythro-pentofuranosyl)- structure](https://www.chemsrc.com/caspic/235/34536-05-5.png)
CAS#:34536-05-5![9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,3,4,7,9-pentazabicyclo[4.3.0]nona-3,7,10-trien-5-one structure](https://www.chemsrc.com/caspic/453/56220-50-9.png)
CAS#:56220-50-9|
In vitro synthesis of 1,N6-etheno-2'-deoxyadenosine and 1,N2-etheno-2'-deoxyguanosine by 2,4-dinitrophenol and 1,3-dinitropyrene in presence of a bacterial nitroreductase.
Environ. Toxicol. 22(2) , 222-7, (2007) The formation of covalent nitro-PAH DNA adducts and nitro-PAH mediated oxidative lesions are two possible mechanisms for the initiation of nitro-PAH carcinogenesis. Sixty-minute incubation of 1,3-dini... |
|
|
Urinary level of 1,N(6) -ethenodeoxyadenosine, a marker of oxidative stress, is associated with salt excretion and omega 6-polyunsaturated fatty acid intake in postmenopausal Japanese women.
Int. J. Cancer 100(1) , 71-5, (2002) Excretion of 1,N(6)-ethenodeoxyadenosine (epsilon dA), a marker for lipid peroxidation (LPO)-derived DNA damage was analyzed in urine of nonsmoking postmenopausal women participating in a dietary inte... |
|
|
Urinary excretion of epsilondA is not predictive of cancer development: a prospective nested case-control study.
Free Radic. Res. 39(1) , 51-3, (2005) Human biomonitoring of the lipid peroxidation DNA modification 1,N6-ethenodeoxyadenosine (epsilondA) excreted into urine is thought to be a potential marker for oxidative stress-related DNA damage and... |
| 1,N6-Etheno-2'-deoxyadenosine |
| 1,N6-ETHENO-2'-DEOXY-ADENOSINE |