N-(p-Coumaroyl) Serotonin

Modify Date: 2024-01-02 10:12:33

N-(p-Coumaroyl) Serotonin structure	Common Name	N-(p-Coumaroyl) Serotonin
	CAS Number	68573-24-0	Molecular Weight	322.35800
	Density	1.346g/cm3	Boiling Point	694.2ºC at 760 mmHg
	Molecular Formula	C₁₉H₁₈N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	373.6ºC

Use of N-(p-Coumaroyl) Serotonin

N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca2+ release from sarcoplasmic reticulum[1]. N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research[2].

Name	N-(p-Coumaroyl) Serotonin
Synonym	More Synonyms

Description	N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca2+ release from sarcoplasmic reticulum[1]. N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research[2].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
References	[1]. Tetsuya Takimoto, et al. Effect of N-(p-coumaroyl)serotonin and N-feruloylserotonin, major anti-atherogenic polyphenols in safflower seed, on vasodilation, proliferation and migration of vascular smooth muscle cells. Mol Nutr Food Res. 2011 Oct;55(10):1561-71. [2]. Shin-ichiro Katsuda, et al. Safflower seed polyphenols (N-(p-coumaroyl)serotonin and N-feruloylserotonin) ameliorate atherosclerosis and distensibility of the aortic wall in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits.Hypertens Res

Description

Related Catalog

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR

Research Areas >> Inflammation/Immunology

Research Areas >> Metabolic Disease

References

[1]. Tetsuya Takimoto, et al. Effect of N-(p-coumaroyl)serotonin and N-feruloylserotonin, major anti-atherogenic polyphenols in safflower seed, on vasodilation, proliferation and migration of vascular smooth muscle cells. Mol Nutr Food Res. 2011 Oct;55(10):1561-71.

[2]. Shin-ichiro Katsuda, et al. Safflower seed polyphenols (N-(p-coumaroyl)serotonin and N-feruloylserotonin) ameliorate atherosclerosis and distensibility of the aortic wall in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits.Hypertens Res

Density	1.346g/cm3
Boiling Point	694.2ºC at 760 mmHg
Molecular Formula	C₁₉H₁₈N₂O₃
Molecular Weight	322.35800
Flash Point	373.6ºC
Exact Mass	322.13200
PSA	85.35000
LogP	3.34210
Index of Refraction	1.73