68573-24-0

68573-24-0 structure

Name: N-(p-Coumaroyl) Serotonin
Chemical Name: N-(p-Coumaroyl) Serotonin
CAS Number: 68573-24-0
Molecular Formula: C₁₉H₁₈N₂O₃
Molecular Weight: 322.35800
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PDGFR
Create Date: 2017-08-12 20:15:49
Modify Date: 2024-01-02 10:12:33
N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca2+ release from sarcoplasmic reticulum[1]. N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research[2].

Name	N-(p-Coumaroyl) Serotonin
Synonyms	ipobscurine A

Description	N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca2+ release from sarcoplasmic reticulum[1]. N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research[2].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
References	[1]. Tetsuya Takimoto, et al. Effect of N-(p-coumaroyl)serotonin and N-feruloylserotonin, major anti-atherogenic polyphenols in safflower seed, on vasodilation, proliferation and migration of vascular smooth muscle cells. Mol Nutr Food Res. 2011 Oct;55(10):1561-71. [2]. Shin-ichiro Katsuda, et al. Safflower seed polyphenols (N-(p-coumaroyl)serotonin and N-feruloylserotonin) ameliorate atherosclerosis and distensibility of the aortic wall in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits.Hypertens Res