4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole

Modify Date: 2024-01-10 20:55:35

4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole Structure
4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole structure
Common Name 4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole
CAS Number 68981-86-2 Molecular Weight 176.21500
Density 1.12 g/cm3 Boiling Point 284.7ºC at 760 mmHg
Molecular Formula C10H12N2O Melting Point N/A
MSDS N/A Flash Point 126ºC

 Names

Name 4,4-dimethyl-2-pyridin-3-yl-5H-1,3-oxazole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.12 g/cm3
Boiling Point 284.7ºC at 760 mmHg
Molecular Formula C10H12N2O
Molecular Weight 176.21500
Flash Point 126ºC
Exact Mass 176.09500
PSA 34.48000
LogP 1.07260
Index of Refraction 1.569

 MSDS

Name: 3-(4 4-Dimethyl-4 5-dihydro-1 3-oxazol-2-yl)pyridine 97% Material Safety Data Sheet
Synonym: 4,5-Dihydro-4,4-dimethyl-2-(3-pyridyl)oxazol
CAS: 68981-86-2
Section 1 - Chemical Product MSDS Name:3-(4 4-Dimethyl-4 5-dihydro-1 3-oxazol-2-yl)pyridine 97% Material Safety Data Sheet
Synonym:4,5-Dihydro-4,4-dimethyl-2-(3-pyridyl)oxazol

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
68981-86-2 3-(4,4-Dimethyl-4,5-dihydro-1,3-oxazol 97% unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 68981-86-2: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H12N2O
Molecular Weight: 176

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents, reducing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 68981-86-2 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
3-(4,4-Dimethyl-4,5-dihydro-1,3-oxazol-2-yl)pyridine - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 68981-86-2: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 68981-86-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 68981-86-2 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi
Safety Phrases S24/25
HS Code 2934999090

 Synthetic Route

~75%

4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole Structure

4,5-dihydro-4,4...

CAS#:68981-86-2

Literature: Vorbruggen; Krolikiewicz Tetrahedron, 1993 , vol. 49, # 41 p. 9353 - 9372

~92%

4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole Structure

4,5-dihydro-4,4...

CAS#:68981-86-2

Literature: Jnaneshwara; Deshpande; Lalithambika; Ravindranathan; Bedekar Tetrahedron Letters, 1998 , vol. 39, # 5-6 p. 459 - 462

~%

4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole Structure

4,5-dihydro-4,4...

CAS#:68981-86-2

Literature: Tetrahedron Letters, , vol. 27, # 43 p. 5269 - 5270

~%

4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole Structure

4,5-dihydro-4,4...

CAS#:68981-86-2

Literature: Tetrahedron Letters, , vol. 27, # 43 p. 5269 - 5270

~77%

4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole Structure

4,5-dihydro-4,4...

CAS#:68981-86-2

Literature: Hauck, Albert E.; Giam, Choo-Seng Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2070 - 2076

~%

4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole Structure

4,5-dihydro-4,4...

CAS#:68981-86-2

Literature: Journal of Organic Chemistry, , vol. 47, # 13 p. 2633 - 2637

~27%

4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole Structure

4,5-dihydro-4,4...

CAS#:68981-86-2

Literature: Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2070 - 2076

~%

4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole Structure

4,5-dihydro-4,4...

CAS#:68981-86-2

Literature: Journal of Organic Chemistry, , vol. 47, # 13 p. 2633 - 2637

~%

4,5-dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole Structure

4,5-dihydro-4,4...

CAS#:68981-86-2

Literature: Synthesis, , # 8 p. 693 - 696

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4,5-Dihydro-4,4-dimethyl-2-(pyrid-3-yl)oxazole
3-(4,4-dimethyl-4,5-dihydro-oxazol-2-yl)-pyridine
4,5-Dihydro-4,4-dimethyl-2-(3-pyridyl)oxazole
4,4-dimethyl-2-(3-pyridyl)-1,3-oxazoline
3-(4,5-dihydro-4,4-dimethyl-2-oxazolyl)pyridine
4,4-Dimethyl-2-(3-pyridyl)-oxazoline
MFCD01313220
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