benzylaza-15-crown-5

Modify Date: 2025-08-23 16:19:43

benzylaza-15-crown-5 Structure
benzylaza-15-crown-5 structure
Common Name benzylaza-15-crown-5
CAS Number 71089-11-7 Molecular Weight 309.40100
Density 1.032g/cm3 Boiling Point 433.4ºC at 760 mmHg
Molecular Formula C17H27NO4 Melting Point N/A
MSDS N/A Flash Point 124.8ºC

 Names

Name 13-benzyl-1,4,7,10-tetraoxa-13-azacyclopentadecane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.032g/cm3
Boiling Point 433.4ºC at 760 mmHg
Molecular Formula C17H27NO4
Molecular Weight 309.40100
Flash Point 124.8ºC
Exact Mass 309.19400
PSA 40.16000
LogP 1.50650
Index of Refraction 1.481
InChIKey NYMNSQXENSRWHC-UHFFFAOYSA-N
SMILES c1ccc(CN2CCOCCOCCOCCOCC2)cc1

 Synthetic Route

~71%

benzylaza-15-crown-5 Structure

benzylaza-15-crown-5

CAS#:71089-11-7

Literature: Luk'yanenko; Basok; Kulygina, E. Yu.; Bogashchenko, T. Yu.; Yakovenko Russian Journal of Organic Chemistry, 2012 , vol. 48, # 10 p. 1345 - 1352 Zh. Org. Khim., 2012 , vol. 48, # 10 p. 1350 - 1357,8

~86%

benzylaza-15-crown-5 Structure

benzylaza-15-crown-5

CAS#:71089-11-7

Literature: Katritzky, Alan R.; Denisko, Olga V.; Belyakov, Sergei A.; Schall, Otto F.; Gokel, George W. Journal of Organic Chemistry, 1996 , vol. 61, # 21 p. 7578 - 7584

~%

benzylaza-15-crown-5 Structure

benzylaza-15-crown-5

CAS#:71089-11-7

Literature: Schultz,R.A.; White,B.D.; Dishong,D.M. Journal of the American Chemical Society, 1985 , vol. 107, p. 6659

~%

benzylaza-15-crown-5 Structure

benzylaza-15-crown-5

CAS#:71089-11-7

Literature: Sakamoto, Hidefumi; Kimura, Keiichi; Koseki, Yasuaki; Matsuo, Mitsunori; Shono, Toshiyuki Journal of Organic Chemistry, 1986 , vol. 51, # 25 p. 4974 - 4979

~%

benzylaza-15-crown-5 Structure

benzylaza-15-crown-5

CAS#:71089-11-7

Literature: Schultz, Rose Ann; Dishong, Dennis M.; Gokel, George W. Tetrahedron Letters, 1981 , vol. 22, # 28 p. 2623 - 2626

~%

benzylaza-15-crown-5 Structure

benzylaza-15-crown-5

CAS#:71089-11-7

Literature: Johnson,M.R. et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 357 - 371

~%

benzylaza-15-crown-5 Structure

benzylaza-15-crown-5

CAS#:71089-11-7

Literature: Johnson,M.R. et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 357 - 371

~%

benzylaza-15-crown-5 Structure

benzylaza-15-crown-5

CAS#:71089-11-7

Literature: Luk'yanenko; Basok; Kulygina, E. Yu.; Bogashchenko, T. Yu.; Yakovenko Russian Journal of Organic Chemistry, 2012 , vol. 48, # 10 p. 1345 - 1352 Zh. Org. Khim., 2012 , vol. 48, # 10 p. 1350 - 1357,8

~%

benzylaza-15-crown-5 Structure

benzylaza-15-crown-5

CAS#:71089-11-7

Literature: Johnson,M.R. et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 357 - 371

 benzylaza-15-crown-5Bioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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 Synonyms

13-(Phenylmethyl)-1,4,7,10-tetraoxa-13-azacyclopentadecane
1-benzyl-1-aza-15-crown-5
Benzylaza-15-crown-5
13-Benzyl-1,4,7,10-tetraoxa-13-aza-cyclopentadecane
1,4,7,10-Tetraoxa-13-azacyclopentadecane,13-(phenylmethyl)
N-Benzyl-aza-15-crown-5
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