Pentaethylene glycol di(p-toluenesulfonate) structure
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Common Name | Pentaethylene glycol di(p-toluenesulfonate) | ||
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CAS Number | 41024-91-3 | Molecular Weight | 546.65100 | |
Density | 1.26 | Boiling Point | 661.4ºC at 760mmHg | |
Molecular Formula | C24H34O10S2 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 353.8ºC | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of Pentaethylene glycol di(p-toluenesulfonate)Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | penta(ethylene glycol) di-p-toluenesulfonate |
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Synonym | More Synonyms |
Description | Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.26 |
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Boiling Point | 661.4ºC at 760mmHg |
Molecular Formula | C24H34O10S2 |
Molecular Weight | 546.65100 |
Flash Point | 353.8ºC |
Exact Mass | 546.15900 |
PSA | 140.42000 |
LogP | 4.64220 |
Index of Refraction | n20/D 1.524(lit.) |
Water Solubility | Not miscible or difficult to mix in water. |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H315-H319-H335 |
Precautionary Statements | P261-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | Xi: Irritant; |
Risk Phrases | 36/37/38 |
Safety Phrases | S24/25 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2909499000 |
~10% Pentaethylene g... CAS#:41024-91-3 |
Literature: Bouzide, Abderrahim; Sauve, Gilles Organic Letters, 2002 , vol. 4, # 14 p. 2329 - 2332 |
~99% Pentaethylene g... CAS#:41024-91-3 |
Literature: Bonger, Kimberly M.; van den Berg, Richard J.B.H.N.; Heitman, Laura H.; IJzerman, Ad P.; Oosterom, Julia; Timmers, Cornelis M.; Overkleeft, Herman S.; van der Marel, Gijsbert A. Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 14 p. 4841 - 4856 |
~% Pentaethylene g... CAS#:41024-91-3 |
Literature: Fenton, David E.; Parkin, Donald; Newton, Roger F. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 449 - 454 |
HS Code | 2909499000 |
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Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
Pure Appl. Chem. 65 , 585, (1993)
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Tetrahedron 49 , 6019, (1993)
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Chem Express 8 , 471, (1993)
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Pentaethylene glycol di-p-toluenesulfonate |
2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate |
MFCD00012204 |