Alizarin

Modify Date: 2024-01-02 18:32:21

Alizarin Structure
Alizarin structure
Common Name Alizarin
CAS Number 72-48-0 Molecular Weight 240.211
Density 1.5±0.1 g/cm3 Boiling Point 430.0±40.0 °C at 760 mmHg
Molecular Formula C14H8O4 Melting Point 287 °C
MSDS Chinese USA Flash Point 228.0±23.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of Alizarin


Alizarin is a natural dye extracted from the roots of madder plant and has been widely used as a pigment in textile fabrics and paintings[1].

 Names

Name alizarin
Synonym More Synonyms

 Alizarin Biological Activity

Description Alizarin is a natural dye extracted from the roots of madder plant and has been widely used as a pigment in textile fabrics and paintings[1].
Related Catalog
References

[1]. Jen M, et al. Ultrafast Intramolecular Proton Transfer of Alizarin Investigated by Femtosecond Stimulated Raman Spectroscopy. J Phys Chem B. 2017 Apr 27;121(16):4129-4136.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 430.0±40.0 °C at 760 mmHg
Melting Point 287 °C
Molecular Formula C14H8O4
Molecular Weight 240.211
Flash Point 228.0±23.8 °C
Exact Mass 240.042252
PSA 74.60000
LogP 4.09
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.733

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CB6580000
CHEMICAL NAME :
Anthraquinone, 1,2-dihydroxy-
CAS REGISTRY NUMBER :
72-48-0
BEILSTEIN REFERENCE NO. :
1914037
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C14-H8-O4
MOLECULAR WEIGHT :
240.22
WISWESSER LINE NOTATION :
L C666 BV IVJ EQ FQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,1,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3295 No. of Facilities: 192 (estimated) No. of Industries: 9 No. of Occupations: 9 No. of Employees: 3003 (estimated) No. of Female Employees: 1199 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/38
Safety Phrases S26-S36-S24/25-S22
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS YO8300000
HS Code 2914700090

 Synthetic Route

 Customs

HS Code 2914690090
Summary 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Articles68

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In this study, the characteristics of the alveolar bone of rats with induced osteoporosis were examined. Thirty-two rats were divided into four groups according to the induction of osteoporosis and dr...

Differentially circulating miRNAs after recent osteoporotic fractures can influence osteogenic differentiation.

Bone 79 , 43-51, (2015)

Osteoporosis is the consequence of altered bone metabolism resulting in the systemic reduction of bone strength and increased risk of fragility fractures. MicroRNAs (miRNAs) regulate gene expression o...

Donor-matched mesenchymal stem cells from knee infrapatellar and subcutaneous adipose tissue of osteoarthritic donors display differential chondrogenic and osteogenic commitment.

Eur. Cell. Mater. 27 , 298-311, (2014)

Cell-based therapies have recently been proposed for the treatment of degenerative articular pathologies, such as early osteoarthritis, with an emphasis on autologous mesenchymal stem cells (MSCs), as...

 Synonyms

Red 83
Pincoffin
Acid Mordant Red B
1,2-Dihydroxy-9,10-anthracenedione
1,2-Anthraquinonediol
Alizarina
Aliazrin
S NO 1141
EINECS 200-782-5
Alizarin
Acid Metachrome Red B
dihydroxyanthraquinone
1,2-Dihydroxy anthraquinone
9,10-Anthracenedione, 1,2-dihydroxy-
1,2-Dihydroxy-9,10-anthraquinone
C Ext. Red 62
Alizarine
D & C Orange No. 15
mordant red 11
MFCD00132540
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