Phentolamine hydrochloride
Modify Date: 2024-01-08 07:14:05
Phentolamine hydrochloride structure
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Common Name | Phentolamine hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 73-05-2 | Molecular Weight | 317.813 | |
| Density | N/A | Boiling Point | 569ºC at 760 mmHg | |
| Molecular Formula | C17H20ClN3O | Melting Point | >230ºC(dec.) | |
| MSDS | Chinese USA | Flash Point | 297.9ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Phentolamine hydrochloridePhentolamine hydrochloride is an orally active adrenergic α receptor-blocking agent[1]. |
| Name | 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol,hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Phentolamine hydrochloride is an orally active adrenergic α receptor-blocking agent[1]. |
|---|---|
| Related Catalog | |
| References |
| Boiling Point | 569ºC at 760 mmHg |
|---|---|
| Melting Point | >230ºC(dec.) |
| Molecular Formula | C17H20ClN3O |
| Molecular Weight | 317.813 |
| Flash Point | 297.9ºC |
| Exact Mass | 317.129486 |
| PSA | 47.86000 |
| LogP | 3.40680 |
| Appearance of Characters | powder | white to off-white |
| Storage condition | -20°C Freezer |
| Water Solubility | methanol: 10 mg/mL, clear, colorless |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | R22 |
| Safety Phrases | S22-S24/25 |
| RIDADR | UN 3249 |
| WGK Germany | 3 |
| RTECS | SL0701000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
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Alteration of vascular reactivity in heart failure: role of phosphodiesterases 3 and 4.
Br. J. Pharmacol. 171(23) , 5361-75, (2014) This study examined the role of the main vascular cAMP-hydrolysing phosphodiesterases (cAMP-PDE) in the regulation of basal vascular tone and relaxation of rat aorta mediated by β-adrenoceptors, follo... |
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Arc-Expressing Neuronal Ensembles Supporting Pattern Separation Require Adrenergic Activity in Anterior Piriform Cortex: An Exploration of Neural Constraints on Learning.
J. Neurosci. 35 , 14070-5, (2015) Arc ensembles in adult rat olfactory bulb (OB) and anterior piriform cortex (PC) were assessed after discrimination training on highly similar odor pairs. Nonselective α- and β-adrenergic antagonists ... |
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Noradrenaline-mediated facilitation of inhibitory synaptic transmission in the dorsal horn of the rat spinal cord involves interlaminar communications.
Eur. J. Neurosci. 42 , 2654-65, (2015) In the dorsal horn of the spinal cord (DH), noradrenaline (NA) is released by axons originating from the locus coeruleus and induces spinal analgesia, the mechanisms of which are poorly understood. He... |
| 3-(((4,5-Dihydro-1H-imidazol-2-yl)methyl)(4-methylphenyl)amino)phenol Hydrochloride |
| 2-(m-Hydroxy-N-p-tolylanilinomethyl)-2-imidazoline Hydrochloride |
| 3-[[(4,5-Dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]phenol Hydrochloride |
| m-(N-(2-Imidazolin-2-ylmethyl)-p-toluidino)phenol monohydrochloride |
| Fentolamine Hydrochloride |
| 2-[N-(m-Hydroxyphenyl)-p-toluidinomethyl]imidazoline Hydrochloride |
| Phenol, 3-(((4,5-dihydro-1H-imidazol-2-yl)methyl)(4-methylphenyl)amino), monohydrochloride |
| phentolamin hydrochloride |
| 3-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol hydrochloride (1:1) |
| 2-[N-(3-Hydroxyphenyl)-p-toluidinomethyl]-2-imidazolidine hydrochloride |
| EINECS 200-793-5 |
| Phentolamine hydrochloride |
| Phentolamine HCl |
| 2-(N'-p-Tolyl-N'-m-hydroxyphenylaminomethyl)-2-imidazoline Hydrochloride |
| Phenol, m-(N-(2-imidazolin-2-ylmethyl)-p-toluidino)-, monohydrochloride (8CI) |
| Prestwick_386 |
| phentolamine |
| MFCD00079268 |
| 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-p-toluidino]-phenol,hydrochloride |
| 50-60-2 (Parent) |
| 3-[N-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-p-toluidino]-phenol,Hydrochlorid |
| Regitine hydrochloride |
| Phenol, 3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-, hydrochloride (1:1) |