3-fluoro-L-tyrosine

Modify Date: 2024-01-11 09:48:41

3-fluoro-L-tyrosine Structure
3-fluoro-L-tyrosine structure
 Common Name 3-fluoro-L-tyrosine
CAS Number 7423-96-3 Molecular Weight 199.18
Density N/A Boiling Point N/A
Molecular Formula C9H10FNO3 Melting Point 260-261°C
MSDS N/A Flash Point >110°C

 Use of 3-fluoro-L-tyrosine


3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT). And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association[1][2].

 Names

Name 3-Fluoro-L-tyrosine
Synonym More Synonyms

 3-fluoro-L-tyrosine Biological Activity

Description 3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT). And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association[1][2].
Related Catalog
References

[1]. Iron A, et al. Action of the phosphonic analogue of tyrosine and of other tyrosine derivatives on rat liver tyrosine aminotransferase. Amino Acids. 1993 Feb;5(1):33-7.  

[2]. Phillips RS, et al. Effects of tyrosine ring fluorination on rates and equilibria of formation of intermediates in the reactions of carbon-carbon lyases. Eur J Biochem. 1997 Mar 1;244(2):658-63.  

 Chemical & Physical Properties

Melting Point 260-261°C
Molecular Formula C9H10FNO3
Molecular Weight 199.18
Flash Point >110°C
Exact Mass 199.06400
PSA 83.55000
LogP 1.18600
Index of Refraction -9 ° (C=1, 1mol/L HCl)
Stability Stable. Incompatible with strong oxidizing agents, strong reducing agents.

 Safety Information

Hazard Codes T
Risk Phrases R25
Safety Phrases S22-S24/25
RIDADR 2811
WGK Germany 3
Packaging Group II
Hazard Class 6.1
HS Code 2922509090

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

(2S)-2-amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid
MFCD00002607
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