UBP 296
Modify Date: 2025-08-20 14:24:28
UBP 296 structure
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Common Name | UBP 296 | ||
|---|---|---|---|---|
| CAS Number | 745055-86-1 | Molecular Weight | 333.30 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 603.0±65.0 °C at 760 mmHg | |
| Molecular Formula | C15H15N3O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 318.5±34.3 °C | |
Use of UBP 296UBP296 is a potent and selective antagonist of GLUK5-containing kainate receptor in the spinal cord. UBP296 reversibly blocks ATPA-induced depressions of synaptic transmission, and affects AMPA receptor-mediated synaptic transmission directly in rat hippocampal slices[1]. |
| Name | 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxo-1-pyrimidinyl]methyl]benzoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | UBP296 is a potent and selective antagonist of GLUK5-containing kainate receptor in the spinal cord. UBP296 reversibly blocks ATPA-induced depressions of synaptic transmission, and affects AMPA receptor-mediated synaptic transmission directly in rat hippocampal slices[1]. |
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| Related Catalog | |
| Target |
IC50: 3.5 ± 1.5 μM (GLUK5), 4.0 ± 0.7 μM (GLUK5/GLUK6), 7.0 ± 5.1 μM (GLUK5/GLUK2)[1] |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 603.0±65.0 °C at 760 mmHg |
| Molecular Formula | C15H15N3O6 |
| Molecular Weight | 333.30 |
| Flash Point | 318.5±34.3 °C |
| Exact Mass | 333.096100 |
| LogP | 1.58 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.659 |
| 2-{[3-(2-Amino-2-carboxyethyl)-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl]methyl}benzoic acid |
| 1(2H)-Pyrimidinepropanoic acid, α-amino-3-[(2-carboxyphenyl)methyl]-3,4-dihydro-2,4-dioxo- |
| 2-[[3-(2-amino-2-carboxyethyl)-2,6-dioxo-1-pyrimidinyl]methyl]benzoic acid |
| 2-{[3-(2-Amino-2-carboxyethyl)-2,6-dioxo-3,6-dihydro-1(2H)-pyrimidinyl]methyl}benzoic acid |