Methylophiopogonanone A
Modify Date: 2024-01-02 09:40:22
Methylophiopogonanone A structure
|
Common Name | Methylophiopogonanone A | ||
|---|---|---|---|---|
| CAS Number | 74805-92-8 | Molecular Weight | 342.343 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 580.1±50.0 °C at 760 mmHg | |
| Molecular Formula | C19H18O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 212.9±23.6 °C | |
Use of Methylophiopogonanone AMethylophiopogonanone A, a major homoisoflavonoid in Ophiopogon japonicas, has both anti-oxidative and anti-inflammatory properties[1]. |
| Name | (3R)-3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydrochromen-4-one |
|---|---|
| Synonym | More Synonyms |
| Description | Methylophiopogonanone A, a major homoisoflavonoid in Ophiopogon japonicas, has both anti-oxidative and anti-inflammatory properties[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Methylophiopogonanone A (MO-A; 10 μmol/L) significantly decreases apoptosis and cleaved caspase-3 expression, elevated the Bcl-2/Bax ratio and restored NO production. Pretreatment with Methylophiopogonanone A (MO-A) markedly increases the activation of PI3K/Akt/eNOS pathway in H9C2 cells subjected to H/R, and the protective effects of MO-A are abolished in the presence of the PI3K inhibitor wortmannin (100 nmol/L)[1]. |
| In Vivo | Methylophiopogonanone A (MO-A;10 mg/kg/d, po) for 2 weeks) protects cardiac function following myocardial I/R injury[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 580.1±50.0 °C at 760 mmHg |
| Molecular Formula | C19H18O6 |
| Molecular Weight | 342.343 |
| Flash Point | 212.9±23.6 °C |
| Exact Mass | 342.110352 |
| PSA | 85.22000 |
| LogP | 5.16 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.654 |
| Hazard Codes | Xi |
|---|
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Methylophiopogo... CAS#:74805-92-8 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 28, # 5 p. 1477 - 1484 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| 3-(1,3-Benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydro-4H-chromen-4-one |
| 4H-1-Benzopyran-4-one, 3-(1,3-benzodioxol-5-ylmethyl)-2,3-dihydro-5,7-dihydroxy-6,8-dimethyl- |
| N1002 |
| Methylophiopogonanone A |
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