- BioBioPha
- China
- Product Name: Methylophiopogonanone A
- Price: ￥Inquiry/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Methylophiopogonanone A
- Price: ￥2400.0/5mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Methylophiopogonanone A
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: R-Methylophiopogonanone A
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
74805-92-8
74805-92-8 structure
- Name: Methylophiopogonanone A
- Chemical Name: (3R)-3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydrochromen-4-one
- CAS Number: 74805-92-8
- Molecular Formula: C19H18O6
- Molecular Weight: 342.343
- Catalog: Natural product Flavonoids
- Create Date: 2018-03-23 08:00:00
- Modify Date: 2024-01-02 09:40:22
-
Methylophiopogonanone A, a major homoisoflavonoid in Ophiopogon japonicas, has both anti-oxidative and anti-inflammatory properties[1].
| Name | (3R)-3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydrochromen-4-one |
|---|---|
| Synonyms |
3-(1,3-Benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 3-(1,3-benzodioxol-5-ylmethyl)-2,3-dihydro-5,7-dihydroxy-6,8-dimethyl- N1002 Methylophiopogonanone A |
| Description | Methylophiopogonanone A, a major homoisoflavonoid in Ophiopogon japonicas, has both anti-oxidative and anti-inflammatory properties[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Methylophiopogonanone A (MO-A; 10 μmol/L) significantly decreases apoptosis and cleaved caspase-3 expression, elevated the Bcl-2/Bax ratio and restored NO production. Pretreatment with Methylophiopogonanone A (MO-A) markedly increases the activation of PI3K/Akt/eNOS pathway in H9C2 cells subjected to H/R, and the protective effects of MO-A are abolished in the presence of the PI3K inhibitor wortmannin (100 nmol/L)[1]. |
| In Vivo | Methylophiopogonanone A (MO-A;10 mg/kg/d, po) for 2 weeks) protects cardiac function following myocardial I/R injury[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 580.1±50.0 °C at 760 mmHg |
| Molecular Formula | C19H18O6 |
| Molecular Weight | 342.343 |
| Flash Point | 212.9±23.6 °C |
| Exact Mass | 342.110352 |
| PSA | 85.22000 |
| LogP | 5.16 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.654 |
| Hazard Codes | Xi |
|---|
|
~%
74805-92-8 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 28, # 5 p. 1477 - 1484 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |