tert-Butylamine

Modify Date: 2026-07-01 12:01:32

tert-Butylamine structure	Common Name	tert-Butylamine
	CAS Number	75-64-9	Molecular Weight	73.13680
	Density	0.696 g/mL at 25 °C(lit.)	Boiling Point	46 °C(lit.)
	Molecular Formula	C₄H₁₁N	Melting Point	-67 °C
	MSDS	Chinese USA	Flash Point	−36.4 °F
	Symbol	GHS02, GHS05, GHS06	Signal Word	Danger

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	tert-butylamine
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	0.696 g/mL at 25 °C(lit.)
Boiling Point	46 °C(lit.)
Melting Point	-67 °C
Molecular Formula	C₄H₁₁N
Molecular Weight	73.13680
Flash Point	−36.4 °F
Exact Mass	73.08910
PSA	26.02000
LogP	1.44390
Vapour density	2.5 (vs air)
Vapour Pressure	5.7 psi ( 20 °C)
Index of Refraction	n20/D 1.377(lit.)
InChIKey	YBRBMKDOPFTVDT-UHFFFAOYSA-N
SMILES	CC(C)(C)N
Stability	Stable. Incompatible with strong acids, strong oxidizing agents. Highly flammable.
Water Solubility	MISCIBLE

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

tert-Butylamine MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EO3330000

CHEMICAL NAME :: tert-Butylamine

CAS REGISTRY NUMBER :: 75-64-9

LAST UPDATED :: 199806

DATA ITEMS CITED :: 16

MOLECULAR FORMULA :: C4-H11-N

MOLECULAR WEIGHT :: 73.16

WISWESSER LINE NOTATION :: ZX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 40 mg/m3/8H-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - visual field changes Sense Organs and Special Senses (Eye) - corneal damage Sense Organs and Special Senses (Eye) - effect, not otherwise specified

REFERENCE :: BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year: 48,26,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 44 mg/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Lungs, Thorax, or Respiration - pulmonary emboli Liver - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0534846

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3800 mg/m3/4H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Lungs, Thorax, or Respiration - dyspnea Blood - hemorrhage

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570798

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 50(12),70,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 378 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 50(12),70,1985

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Gastrointestinal - other changes

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570521

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 375 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 50(12),70,1985 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2010 mg/m3/6H/13W-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538640 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:STEL 5 ppm (15 mg/m3);Skin JAN 1993 OEL-GERMANY:TWA 5 ppm (15 mg/m3);Skin JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (15 mg/m3);STEL 25 ppm (75 mg/m3) JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 14444 No. of Facilities: 219 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1268 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 14444 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4354 (estimated) No. of Female Employees: 729 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS02, GHS05, GHS06
Signal Word	Danger
Hazard Statements	H225-H302-H314-H331-H412
Precautionary Statements	P210-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P403 + P233
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US)
Hazard Codes	F:Flammable
Risk Phrases	R11;R20;R25;R35
Safety Phrases	S16-S26-S36/37/39-S45-S28A
RIDADR	UN 3286 3/PG 2
WGK Germany	1
RTECS	EO3330000
Packaging Group	II
Hazard Class	3
HS Code	29211980

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 8
CAS#:115-11-7 Isobutylene CAS#:28227-42-1 glyoxal bis-N-t... CAS#:109-73-9 n-butylamine CAS#:594-70-7 2-Methyl-2-nitr...
CAS#:16649-50-6 N-tert-butylhyd... CAS#:1118-12-3 TERT-BUTYLUREA CAS#:2658-24-4 Aziridine,2,2-d... CAS#:677-22-5 TERT-BUTYLMAGNE...
DownStream 10
CAS#:109605-04-1 4-tert-butyl-2,... CAS#:4203-80-9 N-tert-butyl-bi... CAS#:109605-10-9 4-tert-butyl-2,... CAS#:108168-88-3 N-tert-butyl-2-...
CAS#:111601-45-7 methyl 2-tert-b... CAS#:1118-32-7 Propanamide,N-(... CAS#:100-02-7 4-Nitrophenol CAS#:67-51-6 3,5-Dimethylpyrazole
CAS#:10560-39-1 1,3,5-tri-tert-... CAS#:104847-07-6 N-t-butyl-2-met...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	29211980

This table lists relevant public references with title, journal and publication metadata for this compound.

Multilayered Thin Films from Boronic Acid-Functional Poly(amido amine)s.

Pharm. Res. 32(9) , 3066-86, (2015)

To investigate the properties of phenylboronic acid-functional poly(amido amine) polymers (BA-PAA) in forming multilayered thin films with poly(vinyl alcohol) (PVA) and chondroitin sulfate (ChS), and ...

Ion chromatography of amylamine and tert.-butylamine in pharmaceuticals.

J. Chromatogr. A. 739(1-2) , 343-9, (1996)

Ion chromatographic (IC) methods have been developed for the assay of amylamine in BMS-181 866-02 and tert.-butylamine (TBA) in BMS-188 494-04. BMS-181 866-02 is the penultimate intermediate in the sy...

[Hygienic standard for tert-butylamine in water].

Gig. Sanit. (12) , 70-1, (1985)

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: Adrenergic beta2 receptor (ADRB2) small molecule agonists, cell-based qHTS assay
Source: 824
External Id: ADRB2293

Name: Adrenergic beta2 receptor (ADRB2) small molecule antagonists, cell-based qHTS assay
Source: 824
External Id: ADRB2713

Total 201, Current Page 1 of 21

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

T-BUTYLAMINE

Butylamine,tert

MFCD00008050

tert-Butylamine

erbumine

tert-C4H9NH2

1-amino-1,1-dimethylethane

butylamine,tertiary

2-methyl-2-propaneamine

1,1-dimethyl-ethylamine

2-amino-2-methylpropane

2-AMINOISOBUTANE

Ter-butyl amine

EINECS 200-888-1

Clavulanate Potassium Impurity 8

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the downstream products of tert-butylamine?

A: Related downstream products(CAS) of tert-butylamine: 109605-04-1;4203-80-9;109605-10-9;108168-88-3;111601-45-7;1118-32-7;100-02-7;67-51-6;10560-39-1;104847-07-6.

Q: What is the melting point of tert-butylamine?

A: Melting point of tert-butylamine is -67 °C.

Q: What is the CAS number of tert-butylamine?

A: CAS number of tert-butylamine is 75-64-9.

Q: What is the polar surface area (PSA) of tert-butylamine?

A: Polar surface area (PSA) of tert-butylamine is 26.02000.

Q: What is the boiling point of tert-butylamine?

A: Boiling point of tert-butylamine is 46 °C(lit.).

Q: What are the upstream materials of tert-butylamine?

A: Related upstream materials(CAS) of tert-butylamine: 115-11-7;28227-42-1;109-73-9;594-70-7;16649-50-6;1118-12-3;2658-24-4;677-22-5.

Q: What is the LogP of tert-butylamine?

A: LogP of tert-butylamine is 1.44390.

Q: What is the InChIKey of tert-butylamine?

A: InChIKey of tert-butylamine is YBRBMKDOPFTVDT-UHFFFAOYSA-N.

Q: What is the molecular formula of tert-butylamine?

A: Molecular formula of tert-butylamine is C4H11N.

Q: What is the English name of tert-butylamine?

A: The English name of tert-butylamine is tert-butylamine.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: tert-Butylamine
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: tert-Butylamine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFUCHEM--75-64-9--High purity tert-Butylamine in stock
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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tert-Butylamine

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