L-Prolinamide

Modify Date: 2026-07-23 20:46:33

L-Prolinamide Structure
L-Prolinamide structure
Common Name L-Prolinamide
CAS Number 7531-52-4 Molecular Weight 114.146
Density 1.1±0.1 g/cm3 Boiling Point 303.6±31.0 °C at 760 mmHg
Molecular Formula C5H10N2O Melting Point 95-97 °C(lit.)
MSDS Chinese USA Flash Point 137.4±24.8 °C

 Use of L-Prolinamide


L-Prolinamide is a proline derivative[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name L-prolinamide
Synonym More Synonyms

 L-Prolinamide Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description L-Prolinamide is a proline derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.1±0.1 g/cm3
Boiling Point 303.6±31.0 °C at 760 mmHg
Melting Point 95-97 °C(lit.)
Molecular Formula C5H10N2O
Molecular Weight 114.146
Flash Point 137.4±24.8 °C
Exact Mass 114.079315
PSA 55.12000
LogP -1.51
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.491
InChIKey VLJNHYLEOZPXFW-BYPYZUCNSA-N
SMILES NC(=O)C1CCCN1

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2933990090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles27

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nat. Chem. Biol. 5 , 45-52, (2009)

Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting tr...

Enantioseparation of amino acids and alpha-hydroxy acids on ligand-exchange continuous beds by capillary electrochromatography.

Electrophoresis 31 , 1517-1520, (2010)

A new chiral stationary phase based on continuous bed (CB) technology using L-prolinamide as a chiral selector was prepared. Its ability for enantioseparation of amino acids and alpha-hydroxy acids by...

d-Glucosamine in a chimeric prolinamide organocatalyst for direct asymmetric aldol addition

Carbohydr. Res. 356 , 273-7, (2012)

O-TBDPS D-glucosamine coupled with l-proline is reported to act as an efficient organocatalyst in the accomplishment of direct aldol reactions. Excellent results, in terms of chemical yields, as well ...

 L-ProlinamideBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Phenotypic growth assay for Mycobacterium tuberculosis grown for 4 days on DPPC, chol...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4649948
Name: Phenotypic growth assay for Mycobacterium tuberculosis grown for 3 days on 7H9, gluco...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4649949
Name: Cell survival assay for modulators of telomere damage signalling
Source: 15378
Target: N/A
External Id: TELO_02
Name: Antibacterial activity against Acinetobacter baumannii ATCC 19606 (CO-ADD:GN_034); MI...
Source: ChEMBL
Target: Acinetobacter baumannii
External Id: CHEMBL4296188
Name: Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 (CO-ADD:GN_042); MIC...
Source: ChEMBL
Target: Pseudomonas aeruginosa
External Id: CHEMBL4296187
Name: Inhibition of nitrogen-starved wild type sigma1278b yeast Gap1-mediated amino acid up...
Source: ChEMBL
Target: General amino-acid permease GAP1
External Id: CHEMBL1228071
Name: qHTS for Inhibitors of Polymerase Kappa
Source: NCGC
Target: DNA polymerase kappa [Homo sapiens]
External Id: PolK100
Name: Antibacterial activity against Pseudomonas aeruginosa PAO397 [PAO1 d(mexAB-oprM) d(me...
Source: ChEMBL
Target: Pseudomonas aeruginosa
External Id: CHEMBL4296802
Name: qHTS for Inhibitors of binding or entry into cells for Marburg Virus
Source: NCGC
Target: gene 4 small orf - Marburg virus
External Id: VSVM-OFFLINE
Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

(S)-Prolinamide
(2S)-2-Pyrrolidinecarboxamide
h-pro-nh2
(S)-Pyrrolidine-2-carboxylic acid amide
MFCD00005253
(2S)-2-Pyrrolidinecarboximidic acid
EINECS 231-397-0
(S)-pyrrolidine-2-carboxamide
L-Prolinamide
(2S)-pyrrolidine-2-carboxamide
Prolinamide
L-proline amide
L-Prolineamide

 L-Prolinamide | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the downstream products of L-prolinamide?
A: Related downstream products(CAS) of L-prolinamide: 34079-31-7;35150-07-3;59936-29-7;214398-99-9;29133-55-9;274901-16-5;24305-27-9;147-85-3;207557-35-5;66411-54-9.
Q: What is the safety information for L-prolinamide?
A: Safety information for L-prolinamide: S22-S24/25.
Q: What is the CAS number of L-prolinamide?
A: CAS number of L-prolinamide is 7531-52-4.
Q: What is the boiling point of L-prolinamide?
A: Boiling point of L-prolinamide is 303.6±31.0 °C at 760 mmHg.
Q: What are the uses of L-prolinamide?
A: Main uses of L-prolinamide: L-Prolinamide is a proline derivative[1].
Q: What is the SMILES notation of L-prolinamide?
A: SMILES notation of L-prolinamide is NC(=O)C1CCCN1.
Q: What is the LogP of L-prolinamide?
A: LogP of L-prolinamide is -1.51.
Q: What is the molecular formula of L-prolinamide?
A: Molecular formula of L-prolinamide is C5H10N2O.
Q: What is the molecular weight of L-prolinamide?
A: Molecular weight of L-prolinamide is 114.146.
Q: What is the melting point of L-prolinamide?
A: Melting point of L-prolinamide is 95-97 °C(lit.).

 L-Prolinamidefactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
Henan Tianfu Chemical Co., Ltd.
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