Hydroxy-PEG4-CH2COOH
Hydroxy-PEG4-CH2COOH structure
|
Common Name | Hydroxy-PEG4-CH2COOH | ||
|---|---|---|---|---|
| CAS Number | 70678-95-4 | Molecular Weight | 252.26200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H20O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Hydroxy-PEG4-CH2COOHHydroxy-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Hydroxy-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C10H20O7 |
|---|---|
| Molecular Weight | 252.26200 |
| Exact Mass | 252.12100 |
| PSA | 94.45000 |
|
~%
Hydroxy-PEG4-CH2COOH CAS#:70678-95-4 |
| Literature: Chen, Bin; Baumeister, Ute; Pelzl, Gerhard; Das, Malay Kumar; Zeng, Xiangbing; Ungar, Goran; Tschierske, Garsten Journal of the American Chemical Society, 2005 , vol. 127, # 47 p. 16578 - 16591 |
|
~99%
Hydroxy-PEG4-CH2COOH CAS#:70678-95-4 |
| Literature: Nakatsuji, Yohji; Kawamura, Norio; Okahara, Mitsuo; Matsushima, Kenji Synthesis, 1981 , # 1 p. 42 - 44 |
|
~58%
Hydroxy-PEG4-CH2COOH CAS#:70678-95-4 |
| Literature: Yamaguchi, Kazuo; Kuboniwa, Hitoshi; Murakami, Nobuya; Hirao, Akira; Nakahama, Swiichi; Yamazaki, Noburo Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 4 p. 1097 - 1101 |
|
~%
Hydroxy-PEG4-CH2COOH CAS#:70678-95-4 |
| Literature: Bostic, Heidi E.; Smith, Matthew D.; Poloukhtine, Andrei A.; Popik, Vladimir V.; Best, Michael D. Chemical Communications, 2012 , vol. 48, # 10 p. 1431 - 1433 |
|
~%
Hydroxy-PEG4-CH2COOH CAS#:70678-95-4 |
| Literature: Nakatsuji, Yohji; Kawamura, Norio; Okahara, Mitsuo; Matsushima, Kenji Synthesis, 1981 , # 1 p. 42 - 44 |
|
~%
Hydroxy-PEG4-CH2COOH CAS#:70678-95-4 |
| Literature: Matsushima,K. et al. Tetrahedron Letters, 1979 , # 36 p. 3445 - 3448 |
![ethyl 2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]acetate structure](https://image.chemsrc.com/caspic/115/154773-34-9.png)
| Carbomethoxytetraethylenglykol |
| 14-hydroxy-3,6,9,12-tetraoxatetradecanoic acid |
| 3,6,9,12-Tetraoxatetradecanoic acid,14-hydroxy |