Cathepsin B inhibitor RC1
Modify Date: 2025-07-04 19:49:57
Cathepsin B inhibitor RC1 structure
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Common Name | Cathepsin B inhibitor RC1 | ||
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| CAS Number | 775573-79-0 | Molecular Weight | 325.537 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H39NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Cathepsin B inhibitor RC1Cathepsin B inhibitor RC1 is a small-molecule that blocks the process of anthrax lethal toxin (LT) cytotoxicity, inhibits enzymatic activity of host cathepsin B that mediates the escape of toxins into the cytoplasm from late endosomes; protects host cells independently of LT concentration and also blocks intoxication by other bacterial exotoxins; reduces the pathogenicity of Human cytomegalovirus and HSV-1 (EC50=12 uM), which relies on cathepsin B protease activity. |
| Name | Cathepsin B inhibitor RC1 |
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| Description | Cathepsin B inhibitor RC1 is a small-molecule that blocks the process of anthrax lethal toxin (LT) cytotoxicity, inhibits enzymatic activity of host cathepsin B that mediates the escape of toxins into the cytoplasm from late endosomes; protects host cells independently of LT concentration and also blocks intoxication by other bacterial exotoxins; reduces the pathogenicity of Human cytomegalovirus and HSV-1 (EC50=12 uM), which relies on cathepsin B protease activity. |
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| References | References 1. Hartmann S, et al. ACS Infect Dis. 2018 May 18. doi: 10.1021/acsinfecdis.8b00053. 2. Gillespie EJ, et al. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):E4904-12. View Related Products by Target Cathepsin |
| Molecular Formula | C20H39NO2 |
|---|---|
| Molecular Weight | 325.537 |