Aurora B inhibitor 1

Modify Date: 2025-09-18 22:40:11

Aurora B inhibitor 1 Structure
Aurora B inhibitor 1 structure
Common Name Aurora B inhibitor 1
CAS Number 937276-52-3 Molecular Weight 529.97
Density N/A Boiling Point N/A
Molecular Formula C25H26ClF2N7O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aurora B inhibitor 1


Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.

 Names

Name Aurora B inhibitor 1

 Aurora B inhibitor 1 Biological Activity

Description Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.
Related Catalog
Target

Aurora B:0.01 μM (Ki)

In Vitro Aurora B inhibitor 1 also inhibits JAK3 and JAK2 with Kis of <0.25 μM and <0.10 μM, respectively[1].
References

[1]. FRAYSSE, Damien, et al. AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS. WO2007059299A1.

 Chemical & Physical Properties

Molecular Formula C25H26ClF2N7O2
Molecular Weight 529.97
InChIKey SLUHYAXFRJQTGB-KRWDZBQOSA-N
SMILES Cc1cc(Nc2cc(N3CC(F)(C4CC4)C3)nc(OC3CCN(C(=O)c4cc(Cl)ccc4F)C3)n2)n[nH]1
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