Aurora B inhibitor 1 structure
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Common Name | Aurora B inhibitor 1 | ||
|---|---|---|---|---|
| CAS Number | 937276-52-3 | Molecular Weight | 529.97 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H26ClF2N7O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Aurora B inhibitor 1Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM. |
| Name | Aurora B inhibitor 1 |
|---|
| Description | Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM. |
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| Related Catalog | |
| Target |
Aurora B:0.01 μM (Ki) |
| In Vitro | Aurora B inhibitor 1 also inhibits JAK3 and JAK2 with Kis of <0.25 μM and <0.10 μM, respectively[1]. |
| References |
[1]. FRAYSSE, Damien, et al. AMINOPYRIMIDINES USEFUL AS KINASE INHIBITORS. WO2007059299A1. |
| Molecular Formula | C25H26ClF2N7O2 |
|---|---|
| Molecular Weight | 529.97 |
| InChIKey | SLUHYAXFRJQTGB-KRWDZBQOSA-N |
| SMILES | Cc1cc(Nc2cc(N3CC(F)(C4CC4)C3)nc(OC3CCN(C(=O)c4cc(Cl)ccc4F)C3)n2)n[nH]1 |