APA modulator T4
Modify Date: 2024-01-19 17:37:32
APA modulator T4 structure
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Common Name | APA modulator T4 | ||
|---|---|---|---|---|
| CAS Number | 785708-33-0 | Molecular Weight | 377.444 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H23N3O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of APA modulator T4APA modulator T4 is a small modulator of alternative polyadenylation (APA) with IC50 of 2.1 uM in reporter assays, modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts; does not inhibits any of the 404 kinases; predominantly induced CR-APA and UTR-APA; APA modulator T4 exhibits high potency and selectivity for APA modulation, inducing a preference for the use of proximal intronic poly(A) CSs with long intron regions through the PABPN1 pathway; APA modulator T4 is a valuable tool for increasing the understanding of the molecular mechanisms of APA and splicing. |
| Name | APA modulator T4 |
|---|
| Description | APA modulator T4 is a small modulator of alternative polyadenylation (APA) with IC50 of 2.1 uM in reporter assays, modulates endogenous APA via nonkinase-mediated pathways and promotes distal-to-proximal (DtoP) APA usage in multiple transcripts; does not inhibits any of the 404 kinases; predominantly induced CR-APA and UTR-APA; APA modulator T4 exhibits high potency and selectivity for APA modulation, inducing a preference for the use of proximal intronic poly(A) CSs with long intron regions through the PABPN1 pathway; APA modulator T4 is a valuable tool for increasing the understanding of the molecular mechanisms of APA and splicing. |
|---|---|
| References | References 1. Araki S, et al. Cell Chem Biol. 2018 Sep 26. pii: S2451-9456(18)30301-5. View Related Products by Target Other Targets |
| Molecular Formula | C22H23N3O3 |
|---|---|
| Molecular Weight | 377.444 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Photoregulin3
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: APA modulator T4
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: APA modulator T4
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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