Calcitriol D6
Modify Date: 2024-01-05 21:05:02
Calcitriol D6 structure
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Common Name | Calcitriol D6 | ||
|---|---|---|---|---|
| CAS Number | 78782-99-7 | Molecular Weight | 422.67300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H38D6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 57.2 °F | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
Use of Calcitriol D6Calcitriol D6 is the deuterated form of Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ), which is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).IC50 value:Target: vitamin D receptorCalcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. |
| Name | (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-7,7,7-trideuterio-6-hydroxy-6-(trideuteriomethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol |
|---|---|
| Synonym | More Synonyms |
| Description | Calcitriol D6 is the deuterated form of Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ), which is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).IC50 value:Target: vitamin D receptorCalcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells. |
|---|---|
| Related Catalog | |
| References |
[2]. Calcitriol in cancer treatment: from the lab to the clinic. Mol.Cancer Ther. 3 373. |
| Molecular Formula | C27H38D6O3 |
|---|---|
| Molecular Weight | 422.67300 |
| Exact Mass | 422.36700 |
| PSA | 60.69000 |
| LogP | 5.70470 |
| Storage condition | 2-8℃ |
| Symbol |
GHS02, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H319 |
| Precautionary Statements | P210-P305 + P351 + P338-P370 + P378-P403 + P235 |
| RIDADR | UN1170 - class 3 - PG 2 - Ethanol, solution |
| Flash Point(F) | 57.2 °F |
| Flash Point(C) | 14 °C |
|
~15%
Calcitriol D6 CAS#:78782-99-7 |
| Literature: Coldwell; Traford; Varley; Kirk; Makin Steroids, 1990 , vol. 55, # 10 p. 418 - 432 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| Soltriol-d6 |
| Rocaltrol-d6 |
| Topitriol-d6 |
| Calcijex-d6 |
| Silkis-d6 |
| Panbonis-d6 |
| Toptriol-d6 |
| Calcitriol-d6 |
| Calcitriol D6 |
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Calcitriol-d6
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
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Price: $960/1mg
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