Ulinastatin

Modify Date: 2024-01-04 09:17:15

Ulinastatin Structure
Ulinastatin structure
Common Name Ulinastatin
CAS Number 80449-31-6 Molecular Weight 220.264
Density 1.2±0.1 g/cm3 Boiling Point 331.5±42.0 °C at 760 mmHg
Molecular Formula C13H16O3 Melting Point N/A
MSDS N/A Flash Point 171.0±16.8 °C

 Use of Ulinastatin


Ulinastatin (Uristatin) is a trypsin and serine protease inhibitor. Ulinastatin is the main protein binding inhibitor of various trypsin, chymotrypsin, and various pancreatic proteases. Ulinastatin shows neuroprotective, anti-inflammatory, anti-apoptotic, anti-oxidant effects[1][2].

 Names

Name 3-(2-Furyl)-2,4-dioxaspiro[5.5]undec-8-ene
Synonym More Synonyms

 Ulinastatin Biological Activity

Description Ulinastatin (Uristatin) is a trypsin and serine protease inhibitor. Ulinastatin is the main protein binding inhibitor of various trypsin, chymotrypsin, and various pancreatic proteases. Ulinastatin shows neuroprotective, anti-inflammatory, anti-apoptotic, anti-oxidant effects[1][2].
Related Catalog
References

[1]. Shangping Fang, et al. Research progress of ulinastatin in the treatment of liver diseases. Int J Clin Exp Pathol. 2020 Nov 1;13(11):2720-2726.  

[2]. Cao C, et al. Ulinastatin Protects Against LPS-Induced Acute Lung Injury By Attenuating TLR4/NF-κB Pathway Activation and Reducing Inflammatory Mediators. Shock. 2018 Nov;50(5):595-605.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 331.5±42.0 °C at 760 mmHg
Molecular Formula C13H16O3
Molecular Weight 220.264
Flash Point 171.0±16.8 °C
Exact Mass 220.109940
LogP 2.87
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.549
Storage condition -20℃

 Synonyms

3-(2-Furyl)-2,4-dioxaspiro[5.5]undec-8-ene
2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-furanyl)-
Ulinastatin
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